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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.4

C82.4

Billable

Follicular lymphoma grade IIIb

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.4 is a billable code used to indicate a diagnosis of follicular lymphoma grade iiib.

Key Diagnostic Point:

Follicular lymphoma grade IIIb is a subtype of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. It is classified as a high-grade lymphoma, indicating a more aggressive disease course compared to lower-grade follicular lymphomas. The disease typically presents with lymphadenopathy, which may be generalized or localized, and can involve extranodal sites. Patients may exhibit B-symptoms, including fever, night sweats, and unexplained weight loss, which are indicative of systemic involvement. Diagnosis is confirmed through histopathological examination, often requiring a biopsy of affected lymph nodes. Staging is crucial for treatment planning and is typically performed using the Ann Arbor system, which assesses the extent of lymph node involvement and any extranodal disease. Treatment protocols may include chemotherapy, immunotherapy, or a combination of both, often tailored to the individual patient’s disease characteristics and overall health status. The prognosis for patients with grade IIIb follicular lymphoma can vary significantly based on factors such as age, performance status, and response to initial therapy.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Differentiation from other lymphoma grades
  • Need for precise staging and assessment of B-symptoms
  • Variability in treatment protocols based on individual patient factors
  • Potential for misclassification with other non-Hodgkin lymphomas

Audit Risk Factors

  • Inadequate documentation of B-symptoms
  • Failure to document staging details
  • Misclassification of lymphoma grade
  • Lack of supporting pathology reports

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Comprehensive documentation of diagnosis, staging, treatment plans, and follow-up care.

Common Clinical Scenarios

Patients presenting with lymphadenopathy and B-symptoms, requiring biopsy and staging.

Billing Considerations

Ensure accurate coding of treatment regimens and monitoring for response to therapy.

Pathology

Documentation Requirements

Detailed pathology reports confirming diagnosis and grade of lymphoma.

Common Clinical Scenarios

Biopsy specimens from lymph nodes or extranodal sites for histological evaluation.

Billing Considerations

Clear documentation of histological findings to support coding and treatment decisions.

Coding Guidelines

Inclusion Criteria

Use C82.4 When
  • Follow official coding guidelines for neoplasms, ensuring accurate documentation of the lymphoma grade and staging
  • Include details of any B
  • symptoms and treatment plans
  • Ensure compliance with the ICD
  • CM coding conventions

Exclusion Criteria

Do NOT use C82.4 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used during treatment of follicular lymphoma grade IIIb.

Documentation Requirements

Document the specific chemotherapy agents used and the patient's response.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy regimens.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and reimbursement processes. It has also enhanced the ability to track treatment outcomes and disease progression.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and reimbursement processes. It has also enhanced the ability to track treatment outcomes and disease progression.

Reimbursement & Billing Impact

reimbursement processes. It has also enhanced the ability to track treatment outcomes and disease progression.

Resources

Clinical References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Coding & Billing References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Frequently Asked Questions

What are the common treatment options for follicular lymphoma grade IIIb?

Common treatment options include chemotherapy regimens such as R-CHOP, immunotherapy with monoclonal antibodies, and in some cases, stem cell transplantation. Treatment is tailored based on the patient's overall health and disease characteristics.