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ICD-10 Guide
ICD-10 CodesC82.45

C82.45

Billable

Follicular lymphoma grade IIIb, lymph nodes of inguinal region and lower limb

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.45 is a billable code used to indicate a diagnosis of follicular lymphoma grade iiib, lymph nodes of inguinal region and lower limb.

Key Diagnostic Point:

Follicular lymphoma is a type of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. Grade IIIb indicates a more aggressive form of the disease, with a higher proportion of large cells compared to grades I and II. This specific code pertains to cases where the lymphoma is localized to the lymph nodes in the inguinal region and lower limb. Patients may present with symptoms such as lymphadenopathy, fatigue, and B-symptoms, which include fever, night sweats, and unexplained weight loss. Diagnosis typically involves imaging studies, biopsy, and histological examination to confirm the presence of neoplastic follicle center cells. Treatment options may include watchful waiting, chemotherapy, immunotherapy, or radiation therapy, depending on the stage of the disease and the patient's overall health. The prognosis varies based on the grade and stage at diagnosis, with grade IIIb generally indicating a more aggressive disease course requiring prompt intervention.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation between lymphoma grades
  • Specificity of lymph node involvement
  • Potential for overlapping symptoms with other conditions
  • Need for accurate staging and treatment documentation

Audit Risk Factors

  • Inadequate documentation of staging
  • Failure to specify lymph node involvement
  • Misclassification of lymphoma grade
  • Lack of documentation for B-symptoms

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Comprehensive documentation of diagnosis, staging, treatment plans, and follow-up care.

Common Clinical Scenarios

Patients presenting with lymphadenopathy, fatigue, and B-symptoms; treatment planning for chemotherapy or immunotherapy.

Billing Considerations

Ensure accurate grading and staging are documented to support the use of C82.45.

Pathology

Documentation Requirements

Detailed pathology reports including histological grading and immunophenotyping.

Common Clinical Scenarios

Biopsy specimens from lymph nodes showing follicular lymphoma characteristics.

Billing Considerations

Pathology reports must clearly indicate the grade and subtype of lymphoma for accurate coding.

Coding Guidelines

Inclusion Criteria

Use C82.45 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is confirmed by appropriate clinical documentation
  • Include details on the grade of lymphoma and specific lymph node involvement

Exclusion Criteria

Do NOT use C82.45 When
  • Exclude codes for other types of lymphomas or conditions that do not meet the criteria for C82

Related ICD-10 Codes

Related CPT Codes

85041CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to monitor blood counts during treatment for lymphoma.

Documentation Requirements

Document the reason for the CBC and any relevant findings.

Specialty Considerations

Hematology/Oncology specialists should ensure that CBC results are correlated with lymphoma treatment.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of lymphomas, including the ability to differentiate between grades and specific lymph node involvement, which enhances the accuracy of patient records and treatment plans.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of lymphomas, including the ability to differentiate between grades and specific lymph node involvement, which enhances the accuracy of patient records and treatment plans.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of lymphomas, including the ability to differentiate between grades and specific lymph node involvement, which enhances the accuracy of patient records and treatment plans.

Resources

Clinical References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Coding & Billing References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Frequently Asked Questions

What are the common symptoms of follicular lymphoma?

Common symptoms include painless swelling of lymph nodes, fatigue, fever, night sweats, and unexplained weight loss, known as B-symptoms.