ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesC82.49

C82.49

Billable

Follicular lymphoma grade IIIb, extranodal and solid organ sites

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.49 is a billable code used to indicate a diagnosis of follicular lymphoma grade iiib, extranodal and solid organ sites.

Key Diagnostic Point:

Follicular lymphoma is a type of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. Grade IIIb indicates a more aggressive form of the disease, where there is a predominance of large cells, often leading to a poorer prognosis compared to lower grades. Extranodal involvement refers to the lymphoma's spread beyond lymph nodes to other organs, such as the liver, spleen, or bone marrow. Patients may present with B-symptoms, which include fever, night sweats, and weight loss, indicating systemic involvement. Diagnosis typically involves imaging studies, biopsy, and immunophenotyping to confirm the presence of malignant B-cells. Treatment protocols may include chemotherapy, immunotherapy, or targeted therapies, depending on the stage and extent of the disease. The management of follicular lymphoma is complex and requires a multidisciplinary approach, often involving oncologists, radiologists, and pathologists.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Differentiation between grades of follicular lymphoma
  • Identification of extranodal involvement
  • Assessment of B-symptoms
  • Staging of the disease

Audit Risk Factors

  • Inadequate documentation of B-symptoms
  • Failure to specify extranodal involvement
  • Incorrect grading of lymphoma
  • Lack of staging information

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Comprehensive documentation of diagnosis, staging, treatment plans, and response to therapy.

Common Clinical Scenarios

Initial diagnosis of lymphoma, treatment planning, and follow-up assessments.

Billing Considerations

Ensure accurate grading and staging are documented to support coding.

Pathology

Documentation Requirements

Detailed pathology reports including histological grading and immunophenotyping results.

Common Clinical Scenarios

Biopsy interpretation and reporting of lymphoma types.

Billing Considerations

Clear communication of findings to support accurate coding by other specialties.

Coding Guidelines

Inclusion Criteria

Use C82.49 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the diagnosis, including the grade and extranodal involvement

Exclusion Criteria

Do NOT use C82.49 When
  • Exclude conditions that do not meet the criteria for this specific code

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used for outpatient chemotherapy administration for patients with follicular lymphoma.

Documentation Requirements

Document the specific chemotherapy regimen and patient response.

Specialty Considerations

Oncology specialists should ensure accurate coding of chemotherapy administration.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and reimbursement processes. The granularity of ICD-10 codes helps in better tracking of treatment outcomes and epidemiological studies.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and reimbursement processes. The granularity of ICD-10 codes helps in better tracking of treatment outcomes and epidemiological studies.

Reimbursement & Billing Impact

reimbursement processes. The granularity of ICD-10 codes helps in better tracking of treatment outcomes and epidemiological studies.

Resources

Clinical References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Coding & Billing References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Frequently Asked Questions

What are the key symptoms of follicular lymphoma grade IIIb?

Key symptoms include B-symptoms such as fever, night sweats, and weight loss, along with lymphadenopathy and possible extranodal involvement.