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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.5

C82.5

Billable

Diffuse follicle center lymphoma

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.5 is a billable code used to indicate a diagnosis of diffuse follicle center lymphoma.

Key Diagnostic Point:

Diffuse follicle center lymphoma (DFCL) is a subtype of non-Hodgkin lymphoma characterized by the proliferation of B-lymphocytes within the follicle centers of lymphoid tissues. This condition typically presents with a diffuse pattern of growth, leading to the infiltration of lymph nodes and potentially other organs. Patients may experience lymphadenopathy, splenomegaly, and systemic symptoms. DFCL is often associated with chromosomal translocations involving the BCL2 gene, contributing to its pathogenesis. Staging of DFCL is crucial for determining prognosis and treatment, typically following the Ann Arbor classification system. B-symptoms, which include fever, night sweats, and weight loss, may be present and are indicative of more advanced disease. Treatment protocols often involve chemotherapy regimens, immunotherapy, and in some cases, stem cell transplantation, depending on the stage and overall health of the patient. Regular follow-up and monitoring for disease progression or recurrence are essential components of patient management.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of clinical presentations and symptoms
  • Need for accurate staging and assessment of B-symptoms
  • Differentiation from other types of lymphomas
  • Potential for co-existing conditions

Audit Risk Factors

  • Inadequate documentation of staging
  • Failure to document B-symptoms
  • Misclassification of lymphoma subtype
  • Incomplete treatment records

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed clinical notes on patient history, physical examination findings, staging, and treatment plans.

Common Clinical Scenarios

Diagnosis of lymphoma, management of chemotherapy side effects, and follow-up care.

Billing Considerations

Ensure accurate documentation of B-symptoms and treatment response to support coding.

Pathology

Documentation Requirements

Histopathological reports confirming the diagnosis and subtype of lymphoma.

Common Clinical Scenarios

Biopsy interpretation and staging of lymphomas.

Billing Considerations

Pathology reports must clearly indicate the subtype to support accurate coding.

Coding Guidelines

Inclusion Criteria

Use C82.5 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the diagnosis, staging, and any associated symptoms
  • Include specific details about treatment and follow
  • up care

Exclusion Criteria

Do NOT use C82.5 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used during treatment of diffuse follicle center lymphoma.

Documentation Requirements

Document the specific chemotherapy regimen and patient response.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy administration.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of lymphoma subtypes, improving the accuracy of data collection and reimbursement processes. C82.5 provides a clear distinction from other lymphoma types, facilitating better patient management and research.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of lymphoma subtypes, improving the accuracy of data collection and reimbursement processes. C82.5 provides a clear distinction from other lymphoma types, facilitating better patient management and research.

Reimbursement & Billing Impact

reimbursement processes. C82.5 provides a clear distinction from other lymphoma types, facilitating better patient management and research.

Resources

Clinical References

  • •
    American Cancer Society - Lymphoma

Coding & Billing References

  • •
    American Cancer Society - Lymphoma

Frequently Asked Questions

What are the common symptoms of diffuse follicle center lymphoma?

Common symptoms include lymphadenopathy, splenomegaly, fever, night sweats, and unexplained weight loss, known as B-symptoms.

How is diffuse follicle center lymphoma staged?

Staging is typically done using the Ann Arbor classification system, which assesses the extent of lymph node involvement and the presence of B-symptoms.

What treatment options are available for diffuse follicle center lymphoma?

Treatment options may include chemotherapy, immunotherapy, and stem cell transplantation, depending on the stage and patient health.