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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.53

C82.53

Billable

Diffuse follicle center lymphoma, intra-abdominal lymph nodes

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.53 is a billable code used to indicate a diagnosis of diffuse follicle center lymphoma, intra-abdominal lymph nodes.

Key Diagnostic Point:

Diffuse follicle center lymphoma (DFCL) is a subtype of non-Hodgkin lymphoma characterized by the proliferation of neoplastic B-cells that arise from follicle center (germinal center) cells. This specific code, C82.53, indicates that the lymphoma is primarily located in the intra-abdominal lymph nodes. Clinically, patients may present with abdominal pain, swelling, or other gastrointestinal symptoms due to lymphadenopathy. DFCL is often associated with advanced disease at diagnosis, and patients may exhibit B-symptoms such as fever, night sweats, and weight loss. Staging of DFCL typically follows the Ann Arbor classification, which assesses the extent of lymph node involvement and the presence of systemic symptoms. Treatment protocols may include chemotherapy, immunotherapy, or targeted therapies, depending on the stage and individual patient factors. Accurate coding is essential for appropriate treatment planning and reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Specificity of the lymphoma subtype
  • Location of lymph node involvement
  • Potential for staging variations
  • Need for detailed documentation of symptoms

Audit Risk Factors

  • Inadequate documentation of lymph node location
  • Failure to document B-symptoms
  • Misclassification of lymphoma subtype
  • Inaccurate staging information

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed clinical notes on diagnosis, staging, treatment plans, and follow-up.

Common Clinical Scenarios

Diagnosis and management of lymphoma, treatment response evaluation, and monitoring for recurrence.

Billing Considerations

Ensure accurate documentation of all symptoms and treatment modalities to support coding.

Pathology

Documentation Requirements

Histopathological reports confirming the diagnosis and subtype of lymphoma.

Common Clinical Scenarios

Review of biopsy specimens and correlation with clinical findings.

Billing Considerations

Pathology reports must clearly state the subtype and location of lymphoma for accurate coding.

Coding Guidelines

Inclusion Criteria

Use C82.53 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the code is used only when the diagnosis is confirmed and documented
  • Include all relevant clinical details, including staging and symptoms, to support the use of this specific code

Exclusion Criteria

Do NOT use C82.53 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used during treatment of diffuse follicle center lymphoma.

Documentation Requirements

Document the specific chemotherapy agent, dosage, and administration details.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy sessions.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of lymphomas, including subtypes and locations, which enhances the accuracy of patient records and treatment plans.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of lymphomas, including subtypes and locations, which enhances the accuracy of patient records and treatment plans.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of lymphomas, including subtypes and locations, which enhances the accuracy of patient records and treatment plans.

Resources

Clinical References

  • •
    American Cancer Society - Lymphoma

Coding & Billing References

  • •
    American Cancer Society - Lymphoma

Frequently Asked Questions

What are the common symptoms of diffuse follicle center lymphoma?

Common symptoms include abdominal pain, swelling, fever, night sweats, and unexplained weight loss. Patients may also present with lymphadenopathy.