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ICD-10 Guide
ICD-10 CodesD48.6

D48.6

Billable

Neoplasm of uncertain behavior of breast

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D48.6 is a billable code used to indicate a diagnosis of neoplasm of uncertain behavior of breast.

Key Diagnostic Point:

D48.6 refers to neoplasms of uncertain behavior specifically located in the breast. These neoplasms are characterized by atypical cellular features that do not clearly classify them as benign or malignant. The uncertainty in behavior implies that while they may not exhibit aggressive characteristics, there is a potential for progression to malignancy. Clinicians often recommend close surveillance, including regular imaging and biopsies, to monitor changes in size or cellular characteristics. The management of these neoplasms typically involves a multidisciplinary approach, including oncologists, radiologists, and pathologists, to ensure appropriate follow-up and intervention if necessary. The diagnosis is often made through imaging studies such as mammography or ultrasound, followed by histopathological examination of biopsy samples. The clinical implications of a diagnosis of D48.6 necessitate careful patient education regarding the potential risks and the importance of adherence to follow-up protocols.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in histological interpretation of neoplasms
  • Need for ongoing surveillance and follow-up documentation
  • Potential for progression to malignancy requiring timely intervention
  • Differentiation from other breast neoplasms with clear behavior classifications

Audit Risk Factors

  • Inadequate documentation of follow-up care
  • Failure to specify the type of neoplasm in clinical notes
  • Lack of clear communication between specialties
  • Inconsistent coding practices among providers

Specialty Focus

Medical Specialties

Oncology

Documentation Requirements

Detailed pathology reports and imaging studies must be included.

Common Clinical Scenarios

Patients with atypical ductal hyperplasia or lobular neoplasia.

Billing Considerations

Ensure that all follow-up plans and patient discussions are documented.

Radiology

Documentation Requirements

Clear imaging reports indicating findings and recommendations for follow-up.

Common Clinical Scenarios

Imaging findings suggestive of neoplasms requiring biopsy.

Billing Considerations

Document any changes in imaging over time to support coding.

Coding Guidelines

Inclusion Criteria

Use D48.6 When
  • According to ICD
  • 10 coding guidelines, D48
  • 6 should be used when the neoplasm's behavior is uncertain and cannot be classified as benign or malignant
  • Coders must ensure that the diagnosis is supported by appropriate clinical documentation and that any follow
  • up plans are clearly outlined

Exclusion Criteria

Do NOT use D48.6 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

19120CPT Code

Excision, breast tumor

Clinical Scenario

Used when a neoplasm of uncertain behavior is excised for further evaluation.

Documentation Requirements

Pathology report must indicate the behavior of the neoplasm.

Specialty Considerations

Oncology and surgical documentation must align for accurate coding.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of neoplasms, including those of uncertain behavior. This specificity aids in better tracking and management of these conditions, improving patient care and outcomes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of neoplasms, including those of uncertain behavior. This specificity aids in better tracking and management of these conditions, improving patient care and outcomes.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of neoplasms, including those of uncertain behavior. This specificity aids in better tracking and management of these conditions, improving patient care and outcomes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What does D48.6 mean?

D48.6 refers to a neoplasm of uncertain behavior located in the breast, indicating that the neoplasm does not have a clear classification as benign or malignant.

How should D48.6 be documented?

Documentation should include detailed pathology reports, imaging studies, and follow-up plans to ensure accurate coding and billing.