Drug-induced folate deficiency anemia
ICD-10 D52.1 is a billable code used to indicate a diagnosis of drug-induced folate deficiency anemia.
Drug-induced folate deficiency anemia (D52.1) is a type of anemia that occurs when the body lacks sufficient folate (vitamin B9) due to the effects of certain medications. Folate is essential for the production of red blood cells, and its deficiency can lead to megaloblastic anemia, characterized by the presence of large, immature red blood cells in the bloodstream. Common medications that may induce folate deficiency include methotrexate, sulfasalazine, and certain anticonvulsants. Symptoms of this condition may include fatigue, weakness, pallor, and shortness of breath. Diagnosis typically involves blood tests to measure hemoglobin levels, red blood cell indices, and serum folate levels. Treatment focuses on discontinuing the offending drug, if possible, and supplementing with folate to restore normal levels. Monitoring and follow-up are essential to ensure resolution of anemia and to prevent recurrence. Understanding the interplay between drug therapy and nutritional deficiencies is crucial for effective management of patients with this condition.
Detailed patient history, medication list, lab results, and treatment plan.
Patients presenting with fatigue and pallor, requiring differential diagnosis of anemia types.
Need for thorough evaluation of medication history and potential drug interactions.
Comprehensive patient history, including dietary habits and medication use.
Routine check-ups revealing signs of anemia in patients on long-term medications.
Awareness of common medications that can induce folate deficiency.
Used to evaluate anemia and monitor treatment response.
Document the reason for the CBC and any relevant findings.
Hematology specialists may require additional tests to assess folate levels.
Common drugs include methotrexate, sulfasalazine, and certain anticonvulsants. These medications can interfere with folate metabolism or absorption, leading to deficiency.
