Sickle-cell thalassemia beta plus with crisis, unspecified
ICD-10 D57.459 is a billable code used to indicate a diagnosis of sickle-cell thalassemia beta plus with crisis, unspecified.
Sickle-cell thalassemia beta plus is a complex hemoglobinopathy resulting from the combination of sickle cell disease and beta-thalassemia. Patients with this condition have a mutation in the beta-globin gene, leading to the production of abnormal hemoglobin (HbS) and reduced production of normal hemoglobin (HbA). This results in a spectrum of clinical manifestations, including hemolytic anemia, vaso-occlusive crises, and increased susceptibility to infections. The term 'with crisis' indicates that the patient is experiencing an acute episode characterized by severe pain due to vaso-occlusion, which can affect various organs. The unspecified nature of the crisis indicates that the specific type or location of the crisis is not documented. Management typically involves pain control, hydration, and sometimes blood transfusions. Genetic counseling is also important for affected individuals and their families, as this condition is inherited in an autosomal recessive pattern. Understanding the interplay between sickle cell disease and thalassemia is crucial for effective treatment and management.
Detailed clinical history, laboratory results, and treatment plans must be documented.
Management of pain crises, blood transfusions, and monitoring for complications.
Ensure accurate representation of the patient's hemoglobin profile and crisis history.
Genetic testing results and family history must be clearly documented.
Counseling for families regarding inheritance patterns and risks.
Documentation should include the implications of genetic findings on treatment options.
Used when a patient with sickle-cell thalassemia beta plus requires a blood transfusion due to severe anemia.
Document the indication for transfusion and the patient's hemoglobin levels.
Hematology specialists should ensure that the transfusion is justified based on clinical guidelines.
The 'with crisis' designation indicates that the patient is experiencing an acute episode of pain or other complications related to their sickle-cell thalassemia beta plus, which requires specific management and documentation.
