Other nonautoimmune hemolytic anemias
ICD-10 D59.4 is a billable code used to indicate a diagnosis of other nonautoimmune hemolytic anemias.
Other nonautoimmune hemolytic anemias encompass a variety of conditions characterized by the premature destruction of red blood cells (RBCs) not driven by autoimmune mechanisms. This category includes hemolytic anemias resulting from inherited enzyme deficiencies, such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, which can lead to hemolysis under oxidative stress. Additionally, thalassemias, which are genetic disorders affecting hemoglobin production, can also result in hemolytic anemia due to ineffective erythropoiesis and increased RBC destruction. Sickle cell disease, another genetic condition, causes RBCs to assume a sickle shape, leading to vaso-occlusive crises and hemolysis. The diagnosis of nonautoimmune hemolytic anemia often requires a thorough clinical evaluation, including a complete blood count (CBC), reticulocyte count, and specific tests to identify underlying enzyme deficiencies or genetic factors. Management may involve addressing the underlying cause, supportive care, and in some cases, blood transfusions. Understanding the nuances of these conditions is crucial for accurate coding and appropriate patient management.
Detailed lab results, family history, and clinical findings.
Diagnosis and management of thalassemia, G6PD deficiency, and sickle cell disease.
Ensure documentation reflects the specific type of hemolytic anemia and any genetic testing performed.
Genetic test results, family pedigree, and clinical assessments.
Evaluation of hereditary hemolytic anemias and counseling for affected families.
Document the genetic basis of the condition to support coding.
Used to evaluate anemia and monitor hemolytic processes.
Document the reason for the CBC and any relevant clinical findings.
Hematology specialists should ensure all relevant lab results are included.
Common causes include genetic disorders like thalassemia and sickle cell disease, as well as enzyme deficiencies such as G6PD deficiency.
