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ICD-10 Guide
ICD-10 CodesChapter 3: Diseases of the blood and blood-forming organsD61

D61

Billable

Other aplastic anemias and other bone marrow failure syndromes

Chapter 3:Diseases of the blood and blood-forming organs

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D61 is a billable code used to indicate a diagnosis of other aplastic anemias and other bone marrow failure syndromes.

Key Diagnostic Point:

Aplastic anemia is a rare but serious condition characterized by the failure of the bone marrow to produce adequate amounts of blood cells, leading to pancytopenia (a reduction in red blood cells, white blood cells, and platelets). This condition can be acquired through various factors such as exposure to toxins, certain medications, viral infections, or autoimmune diseases. Other bone marrow failure syndromes may include conditions like myelodysplastic syndromes and pure red cell aplasia, which also result in inadequate blood cell production but may have different underlying mechanisms. Clinically, patients may present with symptoms such as fatigue, increased susceptibility to infections, and bleeding tendencies due to low platelet counts. Diagnosis typically involves blood tests, bone marrow biopsy, and exclusion of other causes of anemia. Management may include immunosuppressive therapy, blood transfusions, or hematopoietic stem cell transplantation, depending on the severity and underlying cause of the condition.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes leading to aplastic anemia
  • Differentiation from other types of anemia and bone marrow disorders
  • Need for comprehensive documentation of patient history and symptoms
  • Potential for overlapping symptoms with other hematologic conditions

Audit Risk Factors

  • Inadequate documentation of the underlying cause of anemia
  • Failure to specify the type of bone marrow failure syndrome
  • Misclassification of the condition due to overlapping symptoms
  • Lack of supporting lab results or imaging studies

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed patient history, laboratory results, and treatment plans must be documented to support the diagnosis.

Common Clinical Scenarios

Patients presenting with unexplained anemia, recurrent infections, or bleeding episodes.

Billing Considerations

Consideration of the patient's age, comorbidities, and response to previous treatments is crucial for accurate coding.

Oncology

Documentation Requirements

Oncologists must document any malignancies that may contribute to bone marrow failure.

Common Clinical Scenarios

Patients undergoing chemotherapy who develop secondary bone marrow failure.

Billing Considerations

Differentiating between primary and secondary causes of bone marrow failure is essential.

Coding Guidelines

Inclusion Criteria

Use D61 When
  • According to ICD
  • 10 coding guidelines, D61 should be used when the specific type of aplastic anemia or bone marrow failure syndrome is not classified elsewhere
  • Coders must ensure that the documentation supports the diagnosis and that other potential causes of anemia are ruled out

Exclusion Criteria

Do NOT use D61 When
No specific exclusions found.

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate blood cell counts in patients suspected of having aplastic anemia.

Documentation Requirements

Document the indication for the CBC and any relevant clinical findings.

Specialty Considerations

Hematologists should ensure that the CBC results are interpreted in the context of the patient's overall clinical picture.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of aplastic anemia and related conditions, improving the accuracy of data collection and reimbursement processes. Coders must be familiar with the nuances of the new codes to ensure proper documentation and billing.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of aplastic anemia and related conditions, improving the accuracy of data collection and reimbursement processes. Coders must be familiar with the nuances of the new codes to ensure proper documentation and billing.

Reimbursement & Billing Impact

reimbursement processes. Coders must be familiar with the nuances of the new codes to ensure proper documentation and billing.

Resources

Clinical References

  • •
    National Heart, Lung, and Blood Institute - Aplastic Anemia

Coding & Billing References

  • •
    National Heart, Lung, and Blood Institute - Aplastic Anemia

Frequently Asked Questions

What are the common causes of aplastic anemia?

Common causes include exposure to chemicals (like benzene), certain medications (like chemotherapy agents), viral infections (such as hepatitis or HIV), and autoimmune disorders.