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ICD-10 Guide
ICD-10 CodesD61.82

D61.82

Billable

Myelophthisis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D61.82 is a billable code used to indicate a diagnosis of myelophthisis.

Key Diagnostic Point:

Myelophthisis refers to the replacement of bone marrow by abnormal tissue, leading to impaired hematopoiesis and resultant blood cell deficiencies. This condition can arise from various causes, including malignancies, infections, and infiltrative diseases such as fibrosis or granulomatous disease. Aplastic anemia, a specific type of myelophthisis, is characterized by the failure of the bone marrow to produce adequate blood cells, resulting in pancytopenia. Patients may present with symptoms of anemia, such as fatigue and pallor, as well as increased susceptibility to infections and bleeding due to thrombocytopenia. The diagnosis of myelophthisis typically involves a combination of clinical evaluation, blood tests, and bone marrow biopsy, which reveals the extent of marrow infiltration and the presence of abnormal cells. Treatment options may include supportive care, immunosuppressive therapy, or hematopoietic stem cell transplantation, depending on the underlying cause and severity of the condition.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between types of anemia and their underlying causes
  • Need for detailed documentation of bone marrow biopsy results
  • Potential overlap with other hematologic disorders
  • Variability in treatment approaches based on etiology

Audit Risk Factors

  • Inadequate documentation of the underlying cause of myelophthisis
  • Failure to document the results of bone marrow biopsy
  • Misclassification of anemia types
  • Lack of clarity in treatment plans

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed reports of blood tests, bone marrow biopsy findings, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of patients with unexplained anemia or cytopenias.

Billing Considerations

Ensure accurate documentation of the type of anemia and any associated conditions.

Oncology

Documentation Requirements

Comprehensive documentation of cancer history, treatment regimens, and response to therapy.

Common Clinical Scenarios

Management of patients with hematologic malignancies leading to myelophthisis.

Billing Considerations

Document any concurrent treatments that may affect bone marrow function.

Coding Guidelines

Inclusion Criteria

Use D61.82 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the underlying cause of myelophthisis
  • Include relevant clinical findings and treatment plans to support the diagnosis

Exclusion Criteria

Do NOT use D61.82 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate anemia and cytopenias in patients suspected of myelophthisis.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematologists should ensure that the CBC results are interpreted in the context of the patient's overall clinical picture.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of myelophthisis, improving the ability to capture the nuances of this condition and its underlying causes, which enhances data accuracy for treatment and research.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of myelophthisis, improving the ability to capture the nuances of this condition and its underlying causes, which enhances data accuracy for treatment and research.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of myelophthisis, improving the ability to capture the nuances of this condition and its underlying causes, which enhances data accuracy for treatment and research.

Resources

Clinical References

  • •
    American Society of Hematology

Coding & Billing References

  • •
    American Society of Hematology

Frequently Asked Questions

What is myelophthisis?

Myelophthisis is a condition characterized by the replacement of bone marrow by abnormal tissue, leading to impaired blood cell production and various hematologic disorders.