Congenital dyserythropoietic anemia
ICD-10 D64.4 is a billable code used to indicate a diagnosis of congenital dyserythropoietic anemia.
Congenital dyserythropoietic anemia (CDA) is a rare inherited form of anemia characterized by ineffective erythropoiesis and abnormal erythroid precursors in the bone marrow. This condition is often associated with a variety of hematological abnormalities, including macrocytic anemia, reticulocytopenia, and the presence of dysplastic erythroid cells. Patients may present with symptoms such as fatigue, pallor, and splenomegaly. The pathophysiology involves a defect in the erythroid lineage, leading to impaired red blood cell production and increased destruction of erythroid precursors. CDA is classified into several subtypes, with type I being the most common. Diagnosis typically involves a combination of clinical evaluation, laboratory tests including complete blood count (CBC), reticulocyte count, and bone marrow biopsy to assess erythroid morphology. Management may include supportive care, blood transfusions, and in some cases, splenectomy. Understanding the nuances of this condition is crucial for accurate coding and appropriate patient management.
Detailed lab results, including CBC and bone marrow biopsy findings.
Diagnosis and management of patients with unexplained anemia and abnormal bone marrow findings.
Ensure accurate documentation of the subtype of CDA and any associated complications.
Growth and developmental assessments, family history of hematological disorders.
Evaluation of children presenting with chronic anemia and fatigue.
Consideration of genetic counseling for families with a history of congenital anemias.
Used to evaluate anemia in patients suspected of having CDA.
Document the indication for the CBC and any relevant clinical findings.
Hematologists should ensure that the CBC includes reticulocyte counts.
CDA is primarily caused by genetic mutations affecting erythroid progenitor cells, leading to ineffective red blood cell production.
