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ICD-10 Guide
ICD-10 CodesD68.312

D68.312

Billable

Antiphospholipid antibody with hemorrhagic disorder

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D68.312 is a billable code used to indicate a diagnosis of antiphospholipid antibody with hemorrhagic disorder.

Key Diagnostic Point:

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of antiphospholipid antibodies (aPL) that can lead to both thrombotic and hemorrhagic complications. Patients with APS may experience a paradoxical increase in bleeding tendencies due to the interaction of these antibodies with coagulation factors, leading to a bleeding disorder. The presence of aPL can interfere with normal coagulation pathways, resulting in conditions such as thrombocytopenia, where the platelet count is low, further exacerbating the risk of bleeding. Hemorrhagic disorders in APS can manifest as easy bruising, prolonged bleeding from cuts, or more severe bleeding episodes. The management of patients with APS and hemorrhagic disorders often involves careful monitoring and may include anticoagulation therapy, which, while necessary to prevent thrombosis, can also increase the risk of bleeding. Understanding the balance between preventing clot formation and managing bleeding risk is crucial in the treatment of these patients.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • The need for accurate identification of antiphospholipid antibodies.
  • Differentiating between thrombotic and hemorrhagic manifestations.
  • Coexisting conditions such as thrombocytopenia and hemophilia.
  • The requirement for detailed clinical documentation to support the diagnosis.

Audit Risk Factors

  • Inadequate documentation of the presence of antiphospholipid antibodies.
  • Failure to document the specific type of hemorrhagic disorder.
  • Lack of clarity in the relationship between APS and bleeding episodes.
  • Inconsistent coding of related conditions such as thrombocytopenia.

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed lab results showing the presence of antiphospholipid antibodies and platelet counts.

Common Clinical Scenarios

Patients presenting with unexplained bleeding or thrombosis, requiring evaluation for APS.

Billing Considerations

Close monitoring of anticoagulation therapy and its effects on bleeding risk.

Rheumatology

Documentation Requirements

Comprehensive patient history and physical examination findings related to autoimmune symptoms.

Common Clinical Scenarios

Patients with a history of recurrent miscarriages or thrombotic events being evaluated for APS.

Billing Considerations

Understanding the interplay between autoimmune disorders and coagulation abnormalities.

Coding Guidelines

Inclusion Criteria

Use D68.312 When
  • According to ICD
  • 10 guidelines, D68
  • 312 should be used when there is a documented diagnosis of antiphospholipid syndrome with associated hemorrhagic disorder
  • Coders must ensure that the clinical documentation supports the diagnosis and that any related conditions are also coded appropriately

Exclusion Criteria

Do NOT use D68.312 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with platelet count

Clinical Scenario

Used to monitor platelet levels in patients with APS.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematology specialists should ensure that the CBC is interpreted in the context of APS.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like antiphospholipid syndrome, improving the accuracy of diagnoses and treatment tracking. D68.312 provides a clear distinction between patients with APS and those without hemorrhagic complications, which is crucial for appropriate management and reimbursement.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like antiphospholipid syndrome, improving the accuracy of diagnoses and treatment tracking. D68.312 provides a clear distinction between patients with APS and those without hemorrhagic complications, which is crucial for appropriate management and reimbursement.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    Antiphospholipid Syndrome Foundation

Coding & Billing References

  • •
    Antiphospholipid Syndrome Foundation

Frequently Asked Questions

What is the significance of coding D68.312?

Coding D68.312 accurately reflects the presence of antiphospholipid antibodies and associated hemorrhagic disorders, which is crucial for appropriate patient management and reimbursement.