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v1.0.0
ICD-10 Guide
ICD-10 CodesD69.5

D69.5

Billable

Secondary thrombocytopenia

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D69.5 is a billable code used to indicate a diagnosis of secondary thrombocytopenia.

Key Diagnostic Point:

Secondary thrombocytopenia refers to a condition characterized by a decrease in platelet count due to underlying medical conditions or external factors rather than a primary hematological disorder. This condition can arise from various causes, including bone marrow disorders, autoimmune diseases, infections, and the effects of certain medications. In cases of secondary thrombocytopenia, the underlying cause must be identified and treated to manage the platelet count effectively. Common conditions associated with secondary thrombocytopenia include chronic liver disease, hypersplenism, and certain malignancies. Patients may present with symptoms such as easy bruising, prolonged bleeding from cuts, and petechiae. The management of secondary thrombocytopenia often involves addressing the underlying condition, and in some cases, platelet transfusions may be necessary to prevent severe bleeding. It is crucial for healthcare providers to monitor platelet levels and assess the risk of bleeding, especially in patients undergoing anticoagulation therapy or those with coagulation defects. Accurate coding of secondary thrombocytopenia is essential for appropriate treatment and reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes requiring thorough documentation
  • Need for differentiation from primary thrombocytopenia
  • Potential for overlapping symptoms with other bleeding disorders
  • Variability in treatment approaches based on underlying conditions

Audit Risk Factors

  • Inadequate documentation of the underlying cause
  • Failure to specify the type of secondary thrombocytopenia
  • Misclassification with primary thrombocytopenia codes
  • Lack of supporting lab results for platelet counts

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed clinical history, lab results, and treatment plans must be documented.

Common Clinical Scenarios

Patients with autoimmune disorders presenting with low platelet counts.

Billing Considerations

Ensure that the underlying cause is clearly identified and documented.

Oncology

Documentation Requirements

Documentation of cancer diagnosis, treatment regimens, and their effects on platelet counts.

Common Clinical Scenarios

Patients undergoing chemotherapy experiencing thrombocytopenia.

Billing Considerations

Document the relationship between cancer treatment and thrombocytopenia.

Coding Guidelines

Inclusion Criteria

Use D69.5 When
  • According to ICD
  • 10 coding guidelines, secondary thrombocytopenia should be coded only when the underlying cause is documented
  • Coders must ensure that the diagnosis is supported by clinical findings and laboratory results

Exclusion Criteria

Do NOT use D69.5 When
  • Exclusion criteria include primary thrombocytopenia and thrombocytopenia due to known medications without further specification

Related ICD-10 Codes

Related CPT Codes

85027CPT Code

Complete blood count (CBC) with platelet count

Clinical Scenario

Used to monitor platelet levels in patients with secondary thrombocytopenia.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematologists may require more detailed lab interpretations.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of secondary thrombocytopenia, improving the ability to capture the complexity of the condition and its underlying causes. This specificity aids in better patient management and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of secondary thrombocytopenia, improving the ability to capture the complexity of the condition and its underlying causes. This specificity aids in better patient management and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between primary and secondary thrombocytopenia?

Primary thrombocytopenia is a condition where low platelet counts occur without an identifiable underlying cause, often due to bone marrow disorders. Secondary thrombocytopenia, on the other hand, is caused by other medical conditions or factors that affect platelet production or destruction.