Functional disorders of polymorphonuclear neutrophils
Chapter 3:Diseases of the blood and blood-forming organs
ICD-10 D71 is a billable code used to indicate a diagnosis of functional disorders of polymorphonuclear neutrophils.
Functional disorders of polymorphonuclear neutrophils (PMNs) encompass a range of conditions characterized by the impaired function of neutrophils, which are crucial components of the immune system. These disorders can lead to increased susceptibility to infections, as neutrophils play a vital role in the body's defense against pathogens. Neutropenia, a common manifestation, refers to an abnormally low level of neutrophils in the blood, which can be caused by various factors including bone marrow disorders, autoimmune diseases, and certain medications. Patients may present with recurrent infections, delayed wound healing, and other complications related to immune deficiency. Additionally, disorders of the spleen, such as splenomegaly or functional asplenia, can further exacerbate neutrophil dysfunction. The clinical management of these disorders often requires a multidisciplinary approach, including hematology and immunology specialists, to address the underlying causes and improve patient outcomes. Accurate coding is essential for appropriate treatment and reimbursement, as well as for tracking epidemiological trends in these conditions.
Complete blood counts, differential counts, and detailed clinical history.
Patients presenting with recurrent infections, unexplained fevers, or neutropenic episodes.
Ensure that laboratory results clearly indicate neutrophil function and any associated conditions.
Immunological assessments, including specific antibody responses and functional assays.
Patients with autoimmune disorders leading to neutrophil dysfunction or recurrent infections.
Document any immunodeficiencies or related autoimmune conditions that may contribute to neutrophil dysfunction.
Used to evaluate neutrophil levels and function in patients suspected of having D71.
Document the reason for the CBC and any relevant clinical findings.
Hematologists may require additional tests to assess neutrophil function.
Common causes include genetic mutations, autoimmune diseases, infections, and certain medications that impair neutrophil function.
D71 is used for functional disorders where neutrophils are present but not functioning properly, while D70 is for agranulocytosis, where there is a significant reduction in neutrophil count.
