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ICD-10 Guide
ICD-10 CodesChapter 3: Diseases of the blood and blood-forming organsD72

D72

Billable

Other disorders of white blood cells

Chapter 3:Diseases of the blood and blood-forming organs

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D72 is a billable code used to indicate a diagnosis of other disorders of white blood cells.

Key Diagnostic Point:

D72 encompasses a variety of conditions affecting white blood cells (WBCs), which play a crucial role in the immune response. This code is primarily used for disorders that do not fall under more specific categories, such as leukemias or lymphomas. Neutropenia, a significant aspect of D72, is characterized by an abnormally low level of neutrophils, increasing the risk of infections. Causes of neutropenia can include bone marrow disorders, autoimmune diseases, and certain medications. Other white blood cell disorders may involve abnormalities in the production, function, or lifespan of WBCs, leading to conditions such as leukopenia or lymphopenia. Spleen disorders, such as splenomegaly or hypersplenism, can also contribute to these conditions by affecting the sequestration and destruction of blood cells. Immunodeficiencies, whether congenital or acquired, can further complicate the clinical picture, leading to increased susceptibility to infections and other complications. Accurate diagnosis and management of these disorders require a thorough understanding of hematological parameters and the underlying pathophysiology.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes for disorders
  • Overlap with other hematological codes
  • Need for detailed clinical documentation
  • Potential for misdiagnosis or misclassification

Audit Risk Factors

  • Inadequate documentation of clinical findings
  • Failure to specify the type of white blood cell disorder
  • Misclassification of neutropenia severity
  • Lack of supporting lab results

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed lab results, patient history, and treatment plans.

Common Clinical Scenarios

Patients presenting with unexplained infections, fatigue, or abnormal blood counts.

Billing Considerations

Ensure clarity in the type of white blood cell disorder and any associated conditions.

Immunology

Documentation Requirements

Immunological assessments, history of infections, and response to therapies.

Common Clinical Scenarios

Patients with recurrent infections or known immunodeficiencies.

Billing Considerations

Document any underlying causes of immunodeficiency and their impact on WBC function.

Coding Guidelines

Inclusion Criteria

Use D72 When
  • Follow official ICD
  • 10 coding guidelines, ensuring accurate documentation of the specific type of white blood cell disorder
  • Include relevant lab results and clinical findings to support the diagnosis

Exclusion Criteria

Do NOT use D72 When
  • Exclude conditions that are specifically coded elsewhere

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate white blood cell disorders.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematologists may require additional tests based on CBC results.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of white blood cell disorders, improving the ability to capture the nuances of these conditions. D72 provides a broader category for disorders that may not fit neatly into other classifications, allowing for better tracking and management of patient care.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of white blood cell disorders, improving the ability to capture the nuances of these conditions. D72 provides a broader category for disorders that may not fit neatly into other classifications, allowing for better tracking and management of patient care.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of white blood cell disorders, improving the ability to capture the nuances of these conditions. D72 provides a broader category for disorders that may not fit neatly into other classifications, allowing for better tracking and management of patient care.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between D72 and D70?

D72 is a broader category for other disorders of white blood cells, while D70 specifically refers to agranulocytosis, which is a severe form of neutropenia.

When should I use D72?

Use D72 when the patient has a white blood cell disorder that does not fit into more specific categories, ensuring that the documentation supports this diagnosis.