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v1.0.0
ICD-10 Guide
ICD-10 CodesD72.118

D72.118

Billable

Other hypereosinophilic syndrome

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D72.118 is a billable code used to indicate a diagnosis of other hypereosinophilic syndrome.

Key Diagnostic Point:

Other hypereosinophilic syndrome (HES) is characterized by an elevated eosinophil count in the blood, typically exceeding 1,500 eosinophils per microliter, and is associated with various clinical manifestations. This condition can lead to organ damage due to eosinophilic infiltration, particularly affecting the skin, lungs, heart, and gastrointestinal tract. Patients may present with symptoms such as fever, weight loss, fatigue, and respiratory issues. The etiology of HES can be idiopathic or secondary to other conditions, including infections, malignancies, or autoimmune disorders. Neutropenia, a reduction in neutrophils, can occur in some patients, complicating the clinical picture and increasing susceptibility to infections. White blood cell disorders, including leukemias and lymphomas, must be ruled out as they can mimic HES. Spleen disorders may also be present, as splenomegaly can occur due to eosinophilic infiltration. Immunodeficiencies may arise as a consequence of prolonged eosinophilia, necessitating careful monitoring and management. Accurate diagnosis often requires a combination of clinical evaluation, laboratory tests, and imaging studies to assess organ involvement and rule out other causes of eosinophilia.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary causes of hypereosinophilia
  • Need for comprehensive patient history and laboratory results
  • Potential overlap with other hematological disorders
  • Variability in clinical presentation and organ involvement

Audit Risk Factors

  • Inadequate documentation of eosinophil counts
  • Failure to specify the underlying cause of hypereosinophilia
  • Lack of clinical correlation with symptoms
  • Misclassification of related hematological disorders

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed blood work results, including eosinophil counts and differential white blood cell counts.

Common Clinical Scenarios

Patients presenting with unexplained eosinophilia and associated symptoms.

Billing Considerations

Ensure comprehensive documentation of all laboratory findings and clinical assessments.

Immunology

Documentation Requirements

History of immunodeficiencies, autoimmune conditions, and any relevant family history.

Common Clinical Scenarios

Patients with recurrent infections or autoimmune symptoms alongside eosinophilia.

Billing Considerations

Document any immunological assessments performed to rule out underlying conditions.

Coding Guidelines

Inclusion Criteria

Use D72.118 When
  • According to ICD
  • 10 coding guidelines, D72
  • 118 should be used when the hypereosinophilia is not classified elsewhere and is associated with specific clinical manifestations
  • Coders should ensure that the diagnosis is supported by laboratory findings and clinical documentation

Exclusion Criteria

Do NOT use D72.118 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate eosinophil levels in patients suspected of having hypereosinophilia.

Documentation Requirements

Document the reason for the CBC and the results, specifically eosinophil counts.

Specialty Considerations

Hematologists should ensure that differential counts are clearly documented.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of hypereosinophilic syndromes, improving the accuracy of diagnosis and treatment tracking. D72.118 provides a clear distinction from other eosinophilia codes, facilitating better patient management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of hypereosinophilic syndromes, improving the accuracy of diagnosis and treatment tracking. D72.118 provides a clear distinction from other eosinophilia codes, facilitating better patient management.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of hypereosinophilic syndromes, improving the accuracy of diagnosis and treatment tracking. D72.118 provides a clear distinction from other eosinophilia codes, facilitating better patient management.

Resources

Clinical References

  • •
    Hypereosinophilia: A Comprehensive Review

Coding & Billing References

  • •
    Hypereosinophilia: A Comprehensive Review

Frequently Asked Questions

What are the common causes of hypereosinophilia?

Common causes include allergic reactions, infections, malignancies, and autoimmune diseases. It is essential to evaluate the patient thoroughly to determine the underlying cause.