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ICD-10 Guide
ICD-10 CodesD72.820

D72.820

Billable

Lymphocytosis (symptomatic)

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D72.820 is a billable code used to indicate a diagnosis of lymphocytosis (symptomatic).

Key Diagnostic Point:

Lymphocytosis refers to an elevated lymphocyte count in the blood, which can be symptomatic of various underlying conditions. This condition is characterized by an increase in the number of lymphocytes, a type of white blood cell crucial for the immune response. Symptomatic lymphocytosis may present with clinical signs such as fatigue, fever, or recurrent infections, indicating an underlying pathology. It can be associated with a variety of disorders, including infections (viral or bacterial), autoimmune diseases, hematological malignancies, and certain splenic disorders. In cases of neutropenia, where there is a deficiency of neutrophils, the body may compensate by increasing lymphocyte production, leading to lymphocytosis. Additionally, lymphocytosis can occur in the context of immunodeficiencies, where the immune system is compromised, and the body attempts to mount a response to infections. Accurate diagnosis and coding require a thorough understanding of the patient's clinical history, laboratory results, and any associated conditions, as lymphocytosis can be a marker of significant underlying health issues.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary causes of lymphocytosis
  • Understanding the relationship with neutropenia and other white blood cell disorders
  • Identifying associated conditions such as splenic disorders and immunodeficiencies
  • Need for comprehensive clinical documentation to support the diagnosis

Audit Risk Factors

  • Insufficient documentation of symptoms leading to lymphocytosis
  • Failure to document underlying conditions contributing to lymphocytosis
  • Inaccurate coding of related conditions such as neutropenia
  • Lack of clarity in laboratory results supporting the diagnosis

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed blood work results, patient history, and any relevant imaging studies.

Common Clinical Scenarios

Patients presenting with unexplained fatigue, recurrent infections, or abnormal blood counts.

Billing Considerations

Hematologists must ensure that all potential causes of lymphocytosis are explored and documented.

Immunology

Documentation Requirements

Comprehensive immunological assessments, including antibody levels and response to infections.

Common Clinical Scenarios

Patients with known immunodeficiencies presenting with elevated lymphocyte counts.

Billing Considerations

Immunologists should document the patient's immune status and any treatments that may affect lymphocyte levels.

Coding Guidelines

Inclusion Criteria

Use D72.820 When
  • According to ICD
  • 10 coding guidelines, lymphocytosis should be coded based on the presence of symptoms and any underlying conditions
  • It is essential to document the clinical context and any relevant laboratory findings to support the diagnosis

Exclusion Criteria

Do NOT use D72.820 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete Blood Count (CBC) with Differential

Clinical Scenario

Used to evaluate lymphocyte levels in patients presenting with symptoms.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematologists should ensure that the CBC results are interpreted in the context of the patient's overall health.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of lymphocytosis, enabling better tracking of this condition and its associated causes. The granularity of ICD-10 codes helps in understanding the clinical implications and management of lymphocytosis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of lymphocytosis, enabling better tracking of this condition and its associated causes. The granularity of ICD-10 codes helps in understanding the clinical implications and management of lymphocytosis.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of lymphocytosis, enabling better tracking of this condition and its associated causes. The granularity of ICD-10 codes helps in understanding the clinical implications and management of lymphocytosis.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of coding lymphocytosis as symptomatic?

Coding lymphocytosis as symptomatic indicates that the condition is associated with clinical manifestations, which may require further investigation and management. It helps in understanding the patient's overall health status and guides treatment decisions.