ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesD72.822

D72.822

Billable

Plasmacytosis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D72.822 is a billable code used to indicate a diagnosis of plasmacytosis.

Key Diagnostic Point:

Plasmacytosis refers to an abnormal increase in the number of plasma cells in the blood or bone marrow. Plasma cells are a type of white blood cell that produces antibodies, and their proliferation can indicate various underlying conditions, including multiple myeloma, chronic inflammatory diseases, or infections. In cases of plasmacytosis, patients may present with symptoms related to the underlying cause, such as fatigue, bone pain, or recurrent infections due to compromised immune function. The condition can be associated with neutropenia, where there is a decrease in neutrophils, a type of white blood cell crucial for fighting infections. This can complicate the clinical picture, as patients may be at increased risk for infections. Additionally, disorders of the spleen, such as splenomegaly, can affect the production and regulation of blood cells, further complicating the diagnosis and management of plasmacytosis. Immunodeficiencies may also be present, as the overproduction of plasma cells can lead to a dysfunctional immune response, making it essential for healthcare providers to conduct thorough evaluations to determine the underlying cause and appropriate treatment.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary causes of plasmacytosis.
  • Understanding the relationship between plasmacytosis and other hematological disorders.
  • Identifying associated conditions such as neutropenia and splenic disorders.
  • Navigating the documentation requirements for various specialties involved in care.

Audit Risk Factors

  • Inadequate documentation of the underlying cause of plasmacytosis.
  • Failure to document associated conditions like neutropenia or splenic disorders.
  • Misclassification of the type of plasmacytosis (primary vs. secondary).
  • Lack of clarity in laboratory results supporting the diagnosis.

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed lab results, patient history, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of multiple myeloma or other plasma cell disorders.

Billing Considerations

Ensure comprehensive documentation of lab findings and clinical symptoms.

Oncology

Documentation Requirements

Pathology reports, imaging studies, and treatment response assessments.

Common Clinical Scenarios

Management of malignancies associated with plasmacytosis.

Billing Considerations

Document the relationship between plasmacytosis and cancer treatment outcomes.

Coding Guidelines

Inclusion Criteria

Use D72.822 When
  • Follow official coding guidelines for hematological disorders, ensuring accurate documentation of the diagnosis and any associated conditions
  • Include relevant lab results and clinical findings to support the use of D72

Exclusion Criteria

Do NOT use D72.822 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate blood cell counts in patients suspected of having plasmacytosis.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematology specialists should ensure all lab results are clearly documented.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like plasmacytosis, improving the granularity of data for research and treatment outcomes. It has also necessitated more detailed documentation to support the complexity of the diagnosis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like plasmacytosis, improving the granularity of data for research and treatment outcomes. It has also necessitated more detailed documentation to support the complexity of the diagnosis.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like plasmacytosis, improving the granularity of data for research and treatment outcomes. It has also necessitated more detailed documentation to support the complexity of the diagnosis.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the primary cause of plasmacytosis?

Plasmacytosis can be caused by various conditions, including multiple myeloma, chronic infections, and autoimmune diseases. Identifying the underlying cause is crucial for appropriate management.