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ICD-10 Guide
ICD-10 CodesChapter 3: Diseases of the blood and blood-forming organsD76

D76

Billable

Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

Chapter 3:Diseases of the blood and blood-forming organs

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D76 is a billable code used to indicate a diagnosis of other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue.

Key Diagnostic Point:

ICD-10 code D76 encompasses a variety of conditions characterized by the involvement of lymphoreticular and reticulohistiocytic tissues, which play crucial roles in the immune response and hematopoiesis. This code is often used for diseases that do not fit neatly into other categories but still exhibit significant clinical manifestations related to the lymphatic system, spleen, and immune function. Conditions such as neutropenia, which is a reduction in the number of neutrophils leading to increased susceptibility to infections, may be coded under D76 when associated with lymphoreticular tissue involvement. Other white blood cell disorders, including leukopenia and lymphopenia, may also fall under this code if they are linked to underlying lymphoreticular pathologies. Spleen disorders, such as splenomegaly or hypersplenism, can contribute to the clinical picture, affecting blood cell counts and immune function. Immunodeficiencies, whether primary or secondary, may also be represented under this code when they involve the reticulohistiocytic system, leading to a compromised immune response. Accurate coding requires a thorough understanding of the patient's clinical presentation and the underlying pathophysiology.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of conditions that can be coded under D76
  • Need for detailed clinical documentation to support the diagnosis
  • Potential overlap with other codes related to blood disorders
  • Variability in clinical presentation and laboratory findings

Audit Risk Factors

  • Inadequate documentation linking symptoms to lymphoreticular involvement
  • Misuse of D76 when a more specific code is available
  • Failure to document the underlying cause of neutropenia or other blood disorders
  • Inconsistent clinical findings that do not support the diagnosis

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed lab results, patient history, and clinical findings related to blood disorders.

Common Clinical Scenarios

Patients presenting with unexplained neutropenia or leukopenia requiring further investigation.

Billing Considerations

Ensure that all relevant lab tests and their interpretations are documented to support the diagnosis.

Immunology

Documentation Requirements

Comprehensive immunological assessments and history of infections or autoimmune conditions.

Common Clinical Scenarios

Patients with recurrent infections or autoimmune disorders that may indicate an underlying immunodeficiency.

Billing Considerations

Document any immunological tests performed and their results to justify the use of D76.

Coding Guidelines

Inclusion Criteria

Use D76 When
  • According to official coding guidelines, D76 should be used when the condition is specifically linked to lymphoreticular and reticulohistiocytic tissue involvement
  • Coders must ensure that the documentation clearly supports the diagnosis and that any associated conditions are also coded appropriately

Exclusion Criteria

Do NOT use D76 When
  • Exclusion criteria include conditions that are more specifically defined by other codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate blood cell counts in patients suspected of having disorders coded under D76.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematologists should ensure that all relevant lab results are included in the patient's record.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions related to lymphoreticular tissue involvement, improving the accuracy of diagnoses and treatment tracking. D76 provides a means to capture complex cases that may have previously been coded as unspecified.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions related to lymphoreticular tissue involvement, improving the accuracy of diagnoses and treatment tracking. D76 provides a means to capture complex cases that may have previously been coded as unspecified.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions related to lymphoreticular tissue involvement, improving the accuracy of diagnoses and treatment tracking. D76 provides a means to capture complex cases that may have previously been coded as unspecified.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

When should I use D76 instead of a more specific code?

Use D76 when the condition involves lymphoreticular and reticulohistiocytic tissue but does not fit into a more specific category. Ensure that documentation supports this coding choice.