Other histiocytosis syndromes
ICD-10 D76.3 is a billable code used to indicate a diagnosis of other histiocytosis syndromes.
Other histiocytosis syndromes encompass a diverse group of disorders characterized by the abnormal proliferation of histiocytes, which are immune cells that play a crucial role in the body's response to infection and inflammation. These syndromes can manifest with a variety of symptoms, including neutropenia, which is a decrease in the number of neutrophils, a type of white blood cell essential for fighting infections. Patients may also exhibit other white blood cell disorders, splenic disorders, and immunodeficiencies, leading to increased susceptibility to infections and other complications. The clinical presentation can vary widely, with some patients experiencing systemic symptoms such as fever, weight loss, and fatigue, while others may present with localized symptoms depending on the organs involved. Diagnosis often requires a combination of clinical evaluation, laboratory tests, and imaging studies to assess the extent of histiocytic infiltration and its impact on hematologic function. Treatment may involve immunosuppressive therapies, chemotherapy, or targeted therapies, depending on the severity and specific characteristics of the syndrome.
Detailed clinical notes including laboratory results, imaging studies, and treatment plans.
Patients presenting with unexplained neutropenia or splenomegaly.
Ensure that all relevant laboratory tests are documented to support the diagnosis.
Comprehensive immunological assessments and patient history.
Patients with recurrent infections and suspected immunodeficiencies.
Document any immunological evaluations performed to support the diagnosis.
Used to evaluate neutropenia in patients suspected of having histiocytosis.
Document the reason for the CBC and any relevant findings.
Hematology specialists should ensure that all lab results are clearly linked to the diagnosis.
Common symptoms include recurrent infections, splenomegaly, neutropenia, and systemic symptoms such as fever and weight loss.
Diagnosis typically involves clinical evaluation, laboratory tests, imaging studies, and histological confirmation through biopsy.
