Other combined immunodeficiencies
ICD-10 D81.89 is a billable code used to indicate a diagnosis of other combined immunodeficiencies.
Combined immunodeficiencies are a group of disorders characterized by the impaired function of both humoral and cell-mediated immunity. These conditions can lead to increased susceptibility to infections, autoimmune diseases, and malignancies. The term 'other combined immunodeficiencies' encompasses various rare genetic disorders that do not fall under the more commonly recognized categories such as Severe Combined Immunodeficiency (SCID) or X-linked Agammaglobulinemia. Patients may present with recurrent infections, failure to thrive, and other systemic complications. Diagnosis typically involves immunological testing, genetic analysis, and clinical evaluation. Management may include immunoglobulin replacement therapy, prophylactic antibiotics, and in some cases, hematopoietic stem cell transplantation. The complexity of these conditions arises from their heterogeneous nature, requiring a multidisciplinary approach for effective treatment and management.
Detailed immunological assessment results, genetic testing outcomes, and treatment plans.
Patients presenting with recurrent infections, failure to thrive, or autoimmune manifestations.
Ensure comprehensive documentation of all immunological evaluations and treatments to support the diagnosis.
Complete blood counts, bone marrow biopsy results, and any hematologic evaluations.
Patients with hematologic abnormalities associated with immunodeficiencies.
Document any co-existing hematologic conditions that may complicate the immunodeficiency.
Used for obtaining blood samples for immunological testing.
Document the reason for blood collection and any relevant clinical history.
Ensure that the specialty performing the procedure is clearly documented.
Common symptoms include recurrent infections, failure to thrive, autoimmune disorders, and increased susceptibility to certain cancers. Symptoms can vary widely depending on the specific type of immunodeficiency.
