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ICD-10 Guide
ICD-10 CodesD83.2

D83.2

Billable

Common variable immunodeficiency with autoantibodies to B- or T-cells

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D83.2 is a billable code used to indicate a diagnosis of common variable immunodeficiency with autoantibodies to b- or t-cells.

Key Diagnostic Point:

Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder characterized by low levels of serum immunoglobulins and an increased susceptibility to infections. In patients with D83.2, the condition is further complicated by the presence of autoantibodies that target B- or T-cells, leading to autoimmune manifestations. These autoantibodies can disrupt normal immune function, resulting in a range of complications including autoimmune hemolytic anemia, thrombocytopenia, and lymphoproliferative disorders. Clinically, patients may present with recurrent infections, chronic diarrhea, and respiratory issues. Diagnosis typically involves serological testing to assess immunoglobulin levels, along with specific tests for autoantibodies. Management often includes immunoglobulin replacement therapy and immunosuppressive agents to control autoimmune symptoms. Regular monitoring for complications is essential to improve patient outcomes.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Presence of autoantibodies complicates diagnosis and treatment.
  • Requires comprehensive immunological testing for accurate diagnosis.
  • Differentiation from other immunodeficiencies and autoimmune disorders.
  • Potential for multiple co-existing conditions requiring careful documentation.

Audit Risk Factors

  • Inadequate documentation of autoimmune manifestations.
  • Failure to document immunoglobulin levels and treatment plans.
  • Misclassification of related conditions.
  • Inconsistent coding of co-existing autoimmune disorders.

Specialty Focus

Medical Specialties

Immunology

Documentation Requirements

Detailed immunological assessments, including immunoglobulin levels and autoantibody tests.

Common Clinical Scenarios

Patients presenting with recurrent infections and autoimmune symptoms.

Billing Considerations

Ensure comprehensive documentation of all immunological tests and treatment responses.

Hematology

Documentation Requirements

Complete blood counts, reticulocyte counts, and documentation of any hematologic complications.

Common Clinical Scenarios

Patients with autoimmune hemolytic anemia or thrombocytopenia.

Billing Considerations

Document any transfusions or treatments related to hematologic conditions.

Coding Guidelines

Inclusion Criteria

Use D83.2 When
  • Follow ICD
  • CM guidelines for coding immunodeficiencies, ensuring accurate documentation of the presence of autoantibodies and any related complications
  • Include relevant clinical findings and treatment plans

Exclusion Criteria

Do NOT use D83.2 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

36415CPT Code

Collection of venous blood by venipuncture

Clinical Scenario

Used for obtaining blood samples for immunological testing.

Documentation Requirements

Document the reason for blood collection and any relevant patient history.

Specialty Considerations

Ensure that the specialty performing the test is clearly documented.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 allows for more specific coding of immunodeficiencies, including the differentiation of CVID with autoantibodies, which aids in better tracking and management of these complex conditions.

ICD-9 vs ICD-10

The transition to ICD-10 allows for more specific coding of immunodeficiencies, including the differentiation of CVID with autoantibodies, which aids in better tracking and management of these complex conditions.

Reimbursement & Billing Impact

The transition to ICD-10 allows for more specific coding of immunodeficiencies, including the differentiation of CVID with autoantibodies, which aids in better tracking and management of these complex conditions.

Resources

Clinical References

  • •
    American Academy of Allergy, Asthma & Immunology

Coding & Billing References

  • •
    American Academy of Allergy, Asthma & Immunology

Frequently Asked Questions

What are the common symptoms of D83.2?

Common symptoms include recurrent infections, chronic diarrhea, fatigue, and signs of autoimmune disorders such as anemia or thrombocytopenia.

How is D83.2 diagnosed?

Diagnosis is made through clinical evaluation, immunoglobulin level testing, and detection of autoantibodies against B- or T-cells.