Immunodeficiency due to drugs
ICD-10 D84.821 is a billable code used to indicate a diagnosis of immunodeficiency due to drugs.
Immunodeficiency due to drugs refers to a condition where the immune system's ability to fight infections is impaired as a result of pharmacological agents. This can occur due to various medications, including immunosuppressants used in the treatment of autoimmune diseases, chemotherapy agents for cancer, and certain antiviral drugs. The impairment can lead to increased susceptibility to infections, prolonged illness, and complications such as opportunistic infections. Clinically, patients may present with recurrent infections, unusual infections, or infections that are more severe than expected. The diagnosis often requires a thorough patient history to identify the specific drugs involved and their duration of use. Laboratory tests may reveal abnormalities in white blood cell counts, particularly lymphocytes, and other immune markers. Management involves careful monitoring of the patient’s immune status, potential adjustment of drug regimens, and prophylactic measures to prevent infections. Understanding the underlying cause of the immunodeficiency is crucial for effective treatment and management.
Detailed documentation of blood counts, immune function tests, and drug history.
Patients undergoing chemotherapy presenting with recurrent infections.
Ensure that the relationship between drug therapy and immunodeficiency is clearly documented.
Thorough documentation of infection history and immune status.
Patients with opportunistic infections due to immunosuppressive therapy.
Document the specific infections and their relation to the immunodeficiency.
Used to monitor blood cell counts in patients with drug-induced immunodeficiency.
Document the reason for the CBC and any abnormal findings.
Hematologists should ensure correlation between lab results and clinical symptoms.
Common drugs include immunosuppressants like corticosteroids, chemotherapy agents, and certain biologics. Each of these can impair immune function, leading to increased infection risk.
