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v1.0.0
ICD-10 Guide
ICD-10 CodesD89.1

D89.1

Billable

Cryoglobulinemia

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D89.1 is a billable code used to indicate a diagnosis of cryoglobulinemia.

Key Diagnostic Point:

Cryoglobulinemia is a condition characterized by the presence of cryoglobulins, which are abnormal proteins in the blood that precipitate at low temperatures. This condition can lead to various complications, primarily affecting the skin, kidneys, and nervous system. Cryoglobulinemia is often associated with underlying diseases, such as hepatitis C, autoimmune disorders, and certain malignancies. Patients may present with symptoms such as purpura, arthralgia, weakness, and renal impairment. The classification of cryoglobulinemia is typically divided into three types: type I (monoclonal), type II (mixed cryoglobulinemia associated with monoclonal and polyclonal components), and type III (polyclonal). Diagnosis is confirmed through laboratory tests that detect cryoglobulins in the serum, alongside clinical evaluation. Management may involve treating the underlying cause, immunosuppressive therapy, and plasmapheresis in severe cases. Understanding the nuances of cryoglobulinemia is crucial for accurate coding and appropriate patient management.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying conditions that can cause cryoglobulinemia.
  • Need for precise documentation of associated symptoms and laboratory findings.
  • Differentiation between types of cryoglobulinemia for accurate coding.
  • Potential overlap with other hematologic conditions.

Audit Risk Factors

  • Inadequate documentation of underlying conditions.
  • Failure to specify the type of cryoglobulinemia.
  • Lack of laboratory results supporting the diagnosis.
  • Misclassification of symptoms related to cryoglobulinemia.

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed lab results showing cryoglobulin levels and associated symptoms.

Common Clinical Scenarios

Patients presenting with unexplained purpura or renal dysfunction.

Billing Considerations

Ensure that the type of cryoglobulinemia is clearly documented to guide treatment.

Rheumatology

Documentation Requirements

Comprehensive history of autoimmune disorders and related symptoms.

Common Clinical Scenarios

Patients with systemic lupus erythematosus or Sjögren's syndrome presenting with cryoglobulinemia.

Billing Considerations

Document any autoimmune markers and their relevance to the diagnosis.

Coding Guidelines

Inclusion Criteria

Use D89.1 When
  • According to ICD
  • 10 guidelines, D89
  • 1 should be used when cryoglobulinemia is confirmed through laboratory tests
  • It is essential to document the underlying cause and any associated symptoms to ensure accurate coding

Exclusion Criteria

Do NOT use D89.1 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate overall blood health in patients suspected of having cryoglobulinemia.

Documentation Requirements

Document the reason for the CBC and any abnormal findings.

Specialty Considerations

Hematologists should ensure that the CBC results are correlated with cryoglobulinemia symptoms.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of cryoglobulinemia, enabling better tracking of the condition and its associated complications. This specificity aids in research and treatment planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of cryoglobulinemia, enabling better tracking of the condition and its associated complications. This specificity aids in research and treatment planning.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    American Society of Hematology

Coding & Billing References

  • •
    American Society of Hematology

Frequently Asked Questions

What are the common symptoms of cryoglobulinemia?

Common symptoms include purpura, joint pain, weakness, and renal impairment. Symptoms can vary based on the underlying cause and type of cryoglobulinemia.