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ICD-10 Guide
ICD-10 CodesD89.2

D89.2

Billable

Hypergammaglobulinemia, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D89.2 is a billable code used to indicate a diagnosis of hypergammaglobulinemia, unspecified.

Key Diagnostic Point:

Hypergammaglobulinemia is a condition characterized by elevated levels of immunoglobulins in the blood, which can indicate an underlying immune response or disorder. This condition is often associated with chronic infections, autoimmune diseases, and certain malignancies. The increase in immunoglobulins can be a response to various stimuli, including infections, inflammation, or malignancies. Patients may present with symptoms related to the underlying cause, such as fatigue, recurrent infections, or systemic symptoms. The diagnosis of hypergammaglobulinemia is typically made through serum protein electrophoresis, which reveals an abnormal increase in gamma globulins. It is important to note that hypergammaglobulinemia itself is not a disease but rather a laboratory finding that necessitates further investigation to determine the underlying etiology. Treatment is directed at the underlying condition rather than the hypergammaglobulinemia itself. Understanding the context of this condition is crucial for accurate coding and management.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying conditions that can cause hypergammaglobulinemia.
  • Need for comprehensive patient history and laboratory results.
  • Potential for misdiagnosis if underlying conditions are not identified.
  • Variability in clinical presentation and symptoms.

Audit Risk Factors

  • Insufficient documentation of underlying conditions.
  • Inconsistent lab results not correlating with clinical findings.
  • Failure to document the reason for testing.
  • Lack of follow-up on abnormal lab results.

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed lab results, patient history, and clinical findings related to immunoglobulin levels.

Common Clinical Scenarios

Patients presenting with recurrent infections or autoimmune symptoms.

Billing Considerations

Ensure that the underlying cause is investigated and documented.

Rheumatology

Documentation Requirements

Comprehensive assessment of autoimmune symptoms and lab results.

Common Clinical Scenarios

Patients with autoimmune disorders presenting with elevated immunoglobulins.

Billing Considerations

Document the correlation between symptoms and lab findings to support the diagnosis.

Coding Guidelines

Inclusion Criteria

Use D89.2 When
  • According to ICD
  • 10 coding guidelines, hypergammaglobulinemia should be coded when it is documented in the medical record
  • It is essential to ensure that the code reflects the clinical context and any underlying conditions are also coded appropriately

Exclusion Criteria

Do NOT use D89.2 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

84155CPT Code

Immunoglobulin quantitation

Clinical Scenario

Used to assess immunoglobulin levels in patients suspected of having hypergammaglobulinemia.

Documentation Requirements

Document the clinical rationale for testing and any relevant patient history.

Specialty Considerations

Hematologists should ensure that the immunoglobulin levels are interpreted in the context of the patient's overall clinical picture.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like hypergammaglobulinemia, enabling better tracking of underlying causes and improving the accuracy of patient records.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like hypergammaglobulinemia, enabling better tracking of underlying causes and improving the accuracy of patient records.

Reimbursement & Billing Impact

impact treatment and management.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is hypergammaglobulinemia?

Hypergammaglobulinemia is a condition characterized by elevated levels of immunoglobulins in the blood, often indicating an underlying immune response or disorder.

How is hypergammaglobulinemia diagnosed?

It is diagnosed through serum protein electrophoresis, which reveals an abnormal increase in gamma globulins, often requiring further investigation to determine the underlying cause.