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ICD-10 Guide
ICD-10 CodesD89.813

D89.813

Billable

Graft-versus-host disease, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D89.813 is a billable code used to indicate a diagnosis of graft-versus-host disease, unspecified.

Key Diagnostic Point:

Graft-versus-host disease (GVHD) is a serious complication that can occur following allogeneic tissue transplantation, particularly hematopoietic stem cell transplants. It arises when the donor's immune cells recognize the recipient's tissues as foreign and mount an immune response against them. This condition can manifest in various forms, including acute and chronic GVHD, with symptoms affecting the skin, liver, gastrointestinal tract, and other organs. The unspecified designation indicates that the specific type or severity of GVHD has not been clearly defined in the clinical documentation. Clinicians must monitor patients closely for signs of GVHD, as early detection and management are crucial for improving outcomes. Treatment often involves immunosuppressive therapies to mitigate the immune response and prevent further tissue damage. Accurate coding of GVHD is essential for appropriate patient management and reimbursement, as it reflects the complexity of care required for affected individuals.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation and severity of GVHD.
  • Need for precise documentation to differentiate between acute and chronic forms.
  • Potential overlap with other hematologic conditions.
  • Complex treatment regimens that may affect coding.

Audit Risk Factors

  • Inadequate documentation of symptoms and severity.
  • Failure to specify acute vs. chronic GVHD.
  • Lack of follow-up documentation on treatment response.
  • Inconsistent coding practices across different specialties.

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed clinical notes on patient history, transplant details, and symptomatology.

Common Clinical Scenarios

Patients undergoing stem cell transplants who develop GVHD post-procedure.

Billing Considerations

Ensure clear documentation of the type and severity of GVHD for accurate coding.

Transplant Surgery

Documentation Requirements

Operative reports and post-operative follow-up notes detailing the transplant procedure and any complications.

Common Clinical Scenarios

Monitoring patients post-transplant for signs of GVHD.

Billing Considerations

Documentation should include any interventions taken to manage GVHD.

Coding Guidelines

Inclusion Criteria

Use D89.813 When
  • Follow official ICD
  • CM coding guidelines, ensuring that the documentation supports the diagnosis of GVHD
  • Include details on the transplant type and any related complications

Exclusion Criteria

Do NOT use D89.813 When
  • Exclude conditions that may mimic GVHD unless clearly documented

Related ICD-10 Codes

Related CPT Codes

36561CPT Code

Bone marrow transplant

Clinical Scenario

Used in conjunction with D89.813 for patients undergoing transplant procedures.

Documentation Requirements

Operative reports and post-operative care notes detailing the transplant.

Specialty Considerations

Hematology/Oncology specialists should ensure comprehensive documentation of the transplant process.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of GVHD, improving the ability to capture the complexity of this condition. However, the unspecified code may lead to challenges in reimbursement and care management if not documented correctly.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of GVHD, improving the ability to capture the complexity of this condition. However, the unspecified code may lead to challenges in reimbursement and care management if not documented correctly.

Reimbursement & Billing Impact

reimbursement and care management if not documented correctly.

Resources

Clinical References

  • •
    American Society of Hematology

Coding & Billing References

  • •
    American Society of Hematology

Frequently Asked Questions

What is the difference between acute and chronic graft-versus-host disease?

Acute GVHD typically occurs within the first 100 days post-transplant and presents with symptoms such as skin rash, diarrhea, and liver dysfunction. Chronic GVHD can develop later and may involve more systemic symptoms, including fibrosis and chronic inflammation affecting multiple organs.