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ICD-10 Guide
ICD-10 CodesE05.2

E05.2

Billable

Thyrotoxicosis with toxic multinodular goiter

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E05.2 is a billable code used to indicate a diagnosis of thyrotoxicosis with toxic multinodular goiter.

Key Diagnostic Point:

Thyrotoxicosis with toxic multinodular goiter is a condition characterized by the excessive production of thyroid hormones due to the presence of multiple hyperfunctioning nodules within the thyroid gland. This condition is often a result of long-standing iodine deficiency or autonomous nodular growth, leading to hyperthyroidism. Patients may present with symptoms such as weight loss, increased appetite, heat intolerance, palpitations, and anxiety. Physical examination may reveal a visibly enlarged thyroid gland (goiter) with multiple nodules. Diagnosis is typically confirmed through thyroid function tests, which show elevated levels of free thyroxine (FT4) and triiodothyronine (FT3), alongside suppressed thyroid-stimulating hormone (TSH) levels. Imaging studies, such as ultrasound, may be utilized to assess the size and characteristics of the nodules. Management often involves antithyroid medications, radioactive iodine therapy, or surgical intervention, depending on the severity of symptoms and the size of the goiter.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between toxic multinodular goiter and other forms of hyperthyroidism.
  • Understanding the nuances of thyroid function tests and their interpretation.
  • The need for comprehensive documentation of symptoms and laboratory results.
  • Potential overlap with other thyroid-related ICD-10 codes.

Audit Risk Factors

  • Inadequate documentation of thyroid function tests.
  • Failure to specify the presence of nodules in the thyroid.
  • Misclassification of hyperthyroidism types.
  • Lack of clarity in treatment plans and patient follow-up.

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Thorough documentation of thyroid function tests, imaging results, and treatment plans.

Common Clinical Scenarios

Patients presenting with symptoms of hyperthyroidism and a palpable goiter.

Billing Considerations

Endocrinologists must ensure that all relevant lab results are included in the patient's record to support the diagnosis.

Primary Care

Documentation Requirements

Detailed patient history, symptom assessment, and referral notes to specialists if necessary.

Common Clinical Scenarios

Initial evaluation of patients with unexplained weight loss, anxiety, or palpitations.

Billing Considerations

Primary care providers should be aware of the need for timely referrals to endocrinology for further evaluation.

Coding Guidelines

Inclusion Criteria

Use E05.2 When
  • According to ICD
  • 10 guidelines, E05
  • 2 should be used when the patient has documented thyrotoxicosis specifically due to toxic multinodular goiter
  • It is essential to ensure that the diagnosis is supported by appropriate laboratory tests and clinical findings

Exclusion Criteria

Do NOT use E05.2 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

84443CPT Code

Thyroid stimulating hormone (TSH)

Clinical Scenario

Used to assess thyroid function in patients suspected of having E05.2.

Documentation Requirements

Document the reason for the test and the results.

Specialty Considerations

Endocrinologists should ensure that TSH levels are interpreted in the context of FT4 and FT3 levels.

76536CPT Code

Ultrasound, thyroid

Clinical Scenario

Performed to evaluate the size and characteristics of thyroid nodules.

Documentation Requirements

Include ultrasound findings in the patient's record.

Specialty Considerations

Documentation should specify the number and size of nodules.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of thyroid disorders, including E05.2, which helps in better tracking and management of these conditions. It emphasizes the need for detailed documentation and accurate coding practices.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of thyroid disorders, including E05.2, which helps in better tracking and management of these conditions. It emphasizes the need for detailed documentation and accurate coding practices.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of thyroid disorders, including E05.2, which helps in better tracking and management of these conditions. It emphasizes the need for detailed documentation and accurate coding practices.

Resources

Clinical References

  • •
    American Thyroid Association Guidelines

Coding & Billing References

  • •
    American Thyroid Association Guidelines

Frequently Asked Questions

What are the common symptoms of thyrotoxicosis with toxic multinodular goiter?

Common symptoms include weight loss, increased appetite, heat intolerance, palpitations, anxiety, and fatigue. Patients may also present with a visibly enlarged thyroid gland.

How is E05.2 diagnosed?

Diagnosis is made through thyroid function tests showing elevated FT4 and FT3 levels with suppressed TSH, along with imaging studies to assess the presence of multinodular goiter.