ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesE09.21

E09.21

Billable

Drug or chemical induced diabetes mellitus with diabetic nephropathy

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E09.21 is a billable code used to indicate a diagnosis of drug or chemical induced diabetes mellitus with diabetic nephropathy.

Key Diagnostic Point:

E09.21 refers to diabetes mellitus that is induced by drugs or chemicals, specifically characterized by the presence of diabetic nephropathy. This condition arises when certain medications, such as glucocorticoids, antipsychotics, or other agents, lead to insulin resistance or impaired insulin secretion, resulting in elevated blood glucose levels. Diabetic nephropathy, a serious complication of diabetes, manifests as kidney damage due to prolonged hyperglycemia, leading to proteinuria and declining renal function. Patients may present with symptoms such as increased thirst, frequent urination, fatigue, and blurred vision. Management of E09.21 involves controlling blood glucose levels, monitoring renal function, and potentially adjusting or discontinuing the offending medication. Regular assessments of HbA1c levels are crucial to evaluate long-term glycemic control, with target levels typically below 7% for most adults. Insulin therapy may be necessary for some patients, particularly if oral hypoglycemics are ineffective. Close monitoring for other diabetic complications, including retinopathy and neuropathy, is also essential.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Identification of the specific drug or chemical causing diabetes
  • Differentiation from other types of diabetes mellitus
  • Documentation of diabetic nephropathy and its severity
  • Management details regarding insulin therapy and other medications

Audit Risk Factors

  • Inadequate documentation of the drug or chemical responsible
  • Failure to document the presence and severity of nephropathy
  • Incorrect coding of diabetes type
  • Lack of evidence for ongoing management and monitoring

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed medication history, HbA1c levels, and renal function tests.

Common Clinical Scenarios

Patients presenting with new-onset diabetes after starting a new medication.

Billing Considerations

Ensure clear documentation of the relationship between the drug and diabetes onset.

Nephrology

Documentation Requirements

Assessment of kidney function, proteinuria levels, and diabetes management plans.

Common Clinical Scenarios

Patients with diabetes and worsening renal function.

Billing Considerations

Document the stage of nephropathy and any interventions taken.

Coding Guidelines

Inclusion Criteria

Use E09.21 When
  • According to ICD
  • 10 guidelines, E09
  • 21 should be used when diabetes is specifically induced by drugs or chemicals, and there is documented evidence of diabetic nephropathy
  • It is essential to ensure that the documentation supports the diagnosis and that the nephropathy is directly related to the diabetes

Exclusion Criteria

Do NOT use E09.21 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for follow-up visits for diabetes management.

Documentation Requirements

Document patient's diabetes management plan and any changes in medication.

Specialty Considerations

Endocrinologists should ensure comprehensive diabetes management documentation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of drug-induced diabetes, improving the accuracy of diabetes-related statistics and enhancing patient care through better tracking of complications.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of drug-induced diabetes, improving the accuracy of diabetes-related statistics and enhancing patient care through better tracking of complications.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of drug-induced diabetes, improving the accuracy of diabetes-related statistics and enhancing patient care through better tracking of complications.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What medications can induce diabetes mellitus?

Common medications that can induce diabetes include glucocorticoids, certain antipsychotics, and thiazide diuretics. It is important to review the patient's medication history to identify potential causes.