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ICD-10 Guide
ICD-10 CodesE09.321

E09.321

Billable

Drug or chemical induced diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E09.321 is a billable code used to indicate a diagnosis of drug or chemical induced diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema.

Key Diagnostic Point:

E09.321 refers to diabetes mellitus that is induced by drugs or chemicals, characterized by the presence of mild nonproliferative diabetic retinopathy accompanied by macular edema. This condition arises when certain medications, such as glucocorticoids or antipsychotics, lead to insulin resistance or impaired insulin secretion, resulting in elevated blood glucose levels. The mild nonproliferative diabetic retinopathy indicates early changes in the retina due to diabetes, where small blood vessels may leak fluid or bleed, leading to macular edema, which is the accumulation of fluid in the macula, affecting vision. Management of this condition typically involves controlling blood glucose levels through lifestyle modifications, oral hypoglycemic agents, or insulin therapy, while also addressing the ocular complications through regular eye examinations and potential treatments such as laser therapy or anti-VEGF injections. Monitoring HbA1c levels is crucial to assess long-term glycemic control and adjust treatment plans accordingly.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between drug-induced diabetes and other types of diabetes.
  • Identifying the specific drug or chemical responsible for the diabetes.
  • Documenting the severity of retinopathy and presence of macular edema.
  • Understanding the interplay between diabetes management and ocular complications.

Audit Risk Factors

  • Inadequate documentation of the drug or chemical causing diabetes.
  • Failure to document the severity of retinopathy and macular edema.
  • Incorrect coding of diabetes type or complications.
  • Lack of regular monitoring of HbA1c levels.

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed medication history, HbA1c levels, and diabetes management plan.

Common Clinical Scenarios

Patients presenting with new-onset diabetes after starting corticosteroids or antipsychotics.

Billing Considerations

Endocrinologists must ensure comprehensive documentation of the patient's diabetes management and any changes in medication.

Ophthalmology

Documentation Requirements

Detailed retinal examination findings, including the degree of retinopathy and presence of macular edema.

Common Clinical Scenarios

Patients with diabetes presenting for routine eye exams or with vision changes.

Billing Considerations

Ophthalmologists should document the relationship between diabetes control and ocular health.

Coding Guidelines

Inclusion Criteria

Use E09.321 When
  • According to ICD
  • 10 guidelines, E09
  • 321 should be used when diabetes is specifically induced by drugs or chemicals, and it is essential to document the type of drug involved
  • The presence of mild nonproliferative diabetic retinopathy with macular edema must be clearly documented to justify the use of this code

Exclusion Criteria

Do NOT use E09.321 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

92014CPT Code

Ophthalmological examination, comprehensive, established patient

Clinical Scenario

Used for routine eye exams in patients with diabetes.

Documentation Requirements

Document visual acuity, fundoscopic findings, and any treatment plans.

Specialty Considerations

Ophthalmologists should ensure thorough documentation of diabetic changes.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of drug-induced diabetes and its complications, improving the accuracy of claims and facilitating better patient management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of drug-induced diabetes and its complications, improving the accuracy of claims and facilitating better patient management.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What types of drugs can induce diabetes mellitus?

Common drugs that can induce diabetes include glucocorticoids, thiazide diuretics, and certain antipsychotics. These medications can lead to insulin resistance or impaired insulin secretion, resulting in elevated blood glucose levels.