Drug-induced hypopituitarism
ICD-10 E23.1 is a billable code used to indicate a diagnosis of drug-induced hypopituitarism.
Drug-induced hypopituitarism is a condition characterized by the impairment of the pituitary gland's ability to produce hormones due to the influence of certain medications. This condition can lead to deficiencies in one or more of the hormones produced by the pituitary gland, including growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, and gonadotropins. The resulting hormonal imbalances can affect various endocrine glands, including the adrenal glands and thyroid, leading to a cascade of metabolic disturbances. Symptoms may include fatigue, weight gain or loss, decreased libido, and changes in mood. The diagnosis often requires a thorough medication history, as well as hormonal assays to evaluate pituitary function. Treatment typically involves managing the underlying cause, which may include discontinuing the offending drug and providing hormone replacement therapy as needed. Understanding the specific medications that can induce this condition is crucial for effective management and coding.
Detailed medication history, hormone level tests, and clinical symptoms.
Patients presenting with unexplained fatigue, weight changes, or sexual dysfunction after starting new medications.
Endocrinologists must ensure that all relevant hormone levels are tested and documented to support the diagnosis.
Comprehensive patient history, including medication review and symptom assessment.
Patients with chronic illnesses on multiple medications presenting with nonspecific symptoms.
Internal medicine practitioners should be vigilant about the potential endocrine side effects of commonly prescribed medications.
Used to evaluate thyroid function in patients with suspected hypopituitarism.
Document the reason for testing and any relevant symptoms.
Endocrinologists should ensure comprehensive testing of all relevant hormones.
Common medications include glucocorticoids, opioids, and certain psychiatric medications. It's essential to review the patient's complete medication history to identify potential causes.
