Pituitary-dependent Cushing's disease
ICD-10 E24.0 is a billable code used to indicate a diagnosis of pituitary-dependent cushing's disease.
Pituitary-dependent Cushing's disease, also known as Cushing's disease, is a disorder caused by an excess of adrenocorticotropic hormone (ACTH) due to a pituitary adenoma. This benign tumor of the pituitary gland leads to overproduction of cortisol by the adrenal glands, resulting in a range of clinical manifestations. Patients may present with symptoms such as obesity, particularly central obesity, facial rounding (moon facies), skin changes (including easy bruising and striae), hypertension, and glucose intolerance. The condition is characterized by a dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, where the normal feedback mechanisms are disrupted, leading to elevated cortisol levels. Diagnosis typically involves biochemical testing, including 24-hour urinary free cortisol, late-night salivary cortisol, and suppression tests. Imaging studies, such as MRI of the pituitary gland, are essential for identifying the adenoma. Treatment often involves surgical resection of the tumor, and in some cases, radiation therapy or medical management may be necessary. Long-term follow-up is crucial due to the risk of recurrence and the potential for adrenal insufficiency post-treatment.
Detailed hormonal assay results, imaging reports, and clinical symptoms.
Diagnosis and management of Cushing's disease, monitoring treatment response.
Ensure all relevant lab tests and imaging are documented to support the diagnosis.
Operative reports detailing tumor resection and pathology findings.
Surgical intervention for pituitary adenoma.
Document the surgical approach and any complications that may arise.
Used for surgical treatment of pituitary adenoma causing Cushing's disease.
Operative report detailing the procedure and findings.
Endocrinology and neurosurgery must coordinate documentation for accurate coding.
Common symptoms include weight gain, particularly in the abdomen and face, hypertension, easy bruising, and changes in skin texture. Patients may also experience mood changes and increased thirst.
