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v1.0.0
ICD-10 Guide
ICD-10 CodesE27.0

E27.0

Billable

Other adrenocortical overactivity

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E27.0 is a billable code used to indicate a diagnosis of other adrenocortical overactivity.

Key Diagnostic Point:

Other adrenocortical overactivity refers to conditions characterized by excessive production of adrenal hormones, particularly cortisol, which can lead to various metabolic and physiological disturbances. This condition may arise from adrenal tumors, hyperplasia, or ectopic ACTH production. Patients may present with symptoms such as hypertension, obesity, glucose intolerance, and changes in skin pigmentation. The diagnosis often involves biochemical testing to measure hormone levels, imaging studies to identify adrenal masses, and sometimes histological examination. It is crucial to differentiate this condition from other forms of hypercortisolism, such as Cushing's syndrome, which has more specific diagnostic criteria. Management may include surgical intervention, medical therapy, or radiation, depending on the underlying cause. Accurate coding is essential for proper treatment reimbursement and tracking of patient outcomes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes (tumors, hyperplasia, etc.)
  • Need for comprehensive hormone level testing
  • Differentiation from similar conditions (e.g., Cushing's syndrome)
  • Potential for multiple comorbidities affecting treatment

Audit Risk Factors

  • Inadequate documentation of hormone levels
  • Failure to specify the underlying cause of overactivity
  • Misclassification with other endocrine disorders
  • Lack of imaging studies in the medical record

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormone level tests, imaging results, and clinical symptoms must be documented.

Common Clinical Scenarios

Patients presenting with symptoms of hypercortisolism, such as weight gain and hypertension.

Billing Considerations

Ensure all relevant lab results and imaging studies are included in the documentation.

Surgery

Documentation Requirements

Operative reports detailing adrenalectomy or other surgical interventions.

Common Clinical Scenarios

Surgical management of adrenal tumors causing hormone overproduction.

Billing Considerations

Document the indication for surgery and any preoperative evaluations.

Coding Guidelines

Inclusion Criteria

Use E27.0 When
  • Follow official ICD
  • 10 coding guidelines, ensuring accurate documentation of the underlying cause of adrenocortical overactivity
  • Include relevant lab results and imaging studies to support the diagnosis

Exclusion Criteria

Do NOT use E27.0 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

CPT 82533CPT Code

Cortisol, serum

Clinical Scenario

Used to confirm diagnosis of adrenal overactivity.

Documentation Requirements

Document the reason for testing and any relevant clinical findings.

Specialty Considerations

Endocrinologists should ensure comprehensive hormone panels are ordered.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of adrenal disorders, improving the accuracy of diagnoses and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of adrenal disorders, improving the accuracy of diagnoses and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of adrenal disorders, improving the accuracy of diagnoses and treatment tracking.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common symptoms of adrenocortical overactivity?

Common symptoms include hypertension, obesity, glucose intolerance, hirsutism, and changes in skin pigmentation.

How is adrenocortical overactivity diagnosed?

Diagnosis typically involves measuring serum cortisol levels, conducting suppression tests, and performing imaging studies to identify adrenal masses.