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ICD-10 Guide
ICD-10 CodesChapter 4: Endocrine, nutritional and metabolic diseasesE28

E28

Billable

Ovarian dysfunction

Chapter 4:Endocrine, nutritional and metabolic diseases

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E28 is a billable code used to indicate a diagnosis of ovarian dysfunction.

Key Diagnostic Point:

Ovarian dysfunction encompasses a range of disorders affecting the ovaries, which can lead to irregularities in hormone production and menstrual cycles. This condition may arise from various endocrine disorders, including dysfunctions of the parathyroid, pituitary, and adrenal glands. Hormonal imbalances, such as elevated levels of prolactin or androgens, can disrupt normal ovarian function, leading to conditions like polycystic ovary syndrome (PCOS) or premature ovarian failure. The interplay between these endocrine glands is crucial, as they regulate the hypothalamic-pituitary-gonadal axis, which is essential for normal ovarian function. Symptoms may include irregular menstrual cycles, infertility, and signs of hyperandrogenism such as hirsutism or acne. Diagnosis often involves a combination of clinical evaluation, hormonal assays, and imaging studies. Treatment may include hormonal therapies, lifestyle modifications, or surgical interventions depending on the underlying cause of the dysfunction.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes (endocrine disorders)
  • Need for comprehensive hormonal evaluation
  • Potential overlap with other reproductive disorders
  • Variability in clinical presentation

Audit Risk Factors

  • Inadequate documentation of hormonal assays
  • Failure to specify underlying endocrine disorders
  • Misclassification of symptoms related to other conditions
  • Lack of clarity in treatment plans

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormonal profiles, including LH, FSH, estradiol, and testosterone levels.

Common Clinical Scenarios

Patients presenting with amenorrhea, oligomenorrhea, or signs of hyperandrogenism.

Billing Considerations

Ensure all relevant endocrine evaluations are documented to support the diagnosis.

Gynecology

Documentation Requirements

Menstrual history, physical examination findings, and any imaging studies performed.

Common Clinical Scenarios

Evaluation of infertility or menstrual irregularities in women of reproductive age.

Billing Considerations

Document any associated reproductive health issues to provide a comprehensive clinical picture.

Coding Guidelines

Inclusion Criteria

Use E28 When
  • Follow official ICD
  • 10 guidelines for coding E28, ensuring accurate documentation of the underlying causes and associated symptoms
  • Include any relevant laboratory results and imaging studies to support the diagnosis

Exclusion Criteria

Do NOT use E28 When
No specific exclusions found.

Related CPT Codes

83001CPT Code

Estradiol test

Clinical Scenario

Used to evaluate ovarian function in patients with menstrual irregularities.

Documentation Requirements

Document the reason for testing and any relevant clinical findings.

Specialty Considerations

Endocrinologists should ensure comprehensive hormonal panels are ordered.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of ovarian dysfunction, enabling better tracking of related conditions and improving the accuracy of treatment data.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of ovarian dysfunction, enabling better tracking of related conditions and improving the accuracy of treatment data.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of ovarian dysfunction, enabling better tracking of related conditions and improving the accuracy of treatment data.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of ovarian dysfunction?

Common causes include polycystic ovary syndrome (PCOS), premature ovarian failure, hyperprolactinemia, and adrenal disorders. Each of these conditions can lead to hormonal imbalances affecting ovarian function.