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ICD-10 Guide
ICD-10 CodesE28.2

E28.2

Billable

Polycystic ovarian syndrome

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E28.2 is a billable code used to indicate a diagnosis of polycystic ovarian syndrome.

Key Diagnostic Point:

Polycystic ovarian syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age, characterized by a combination of symptoms including irregular menstrual cycles, hyperandrogenism (excess male hormones), and polycystic ovaries. The pathophysiology of PCOS is complex and involves hormonal imbalances, particularly elevated levels of insulin and androgens, which can lead to various metabolic and reproductive issues. Women with PCOS may experience symptoms such as weight gain, acne, hirsutism (excessive hair growth), and infertility. The condition is also associated with an increased risk of developing type 2 diabetes, cardiovascular disease, and endometrial cancer. Diagnosis typically involves a combination of clinical evaluation, hormonal assessments, and imaging studies such as ultrasound to identify the presence of multiple cysts on the ovaries. Management of PCOS often includes lifestyle modifications, hormonal therapies, and medications to address specific symptoms and reduce long-term health risks.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in symptom presentation among patients
  • Need for comprehensive hormonal evaluation
  • Potential overlap with other endocrine disorders
  • Documentation of associated conditions (e.g., obesity, insulin resistance)

Audit Risk Factors

  • Inadequate documentation of symptoms and hormonal levels
  • Failure to document associated conditions
  • Misclassification of PCOS severity
  • Lack of imaging results in the medical record

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormonal profiles, imaging results, and symptomatology.

Common Clinical Scenarios

Evaluation of patients with irregular menstrual cycles and signs of hyperandrogenism.

Billing Considerations

Endocrinologists must ensure comprehensive documentation of all hormonal assessments and related metabolic conditions.

Gynecology

Documentation Requirements

Menstrual history, physical examination findings, and ultrasound results.

Common Clinical Scenarios

Management of infertility in women diagnosed with PCOS.

Billing Considerations

Gynecologists should document the impact of PCOS on reproductive health and any treatments provided.

Coding Guidelines

Inclusion Criteria

Use E28.2 When
  • According to ICD
  • 10 guidelines, E28
  • 2 should be used when a patient presents with symptoms consistent with PCOS, supported by clinical findings and diagnostic imaging

Exclusion Criteria

Do NOT use E28.2 When
  • Exclusion criteria include other causes of hyperandrogenism or menstrual irregularities

Related ICD-10 Codes

Related CPT Codes

58300CPT Code

Ultrasound, pelvic, transabdominal

Clinical Scenario

Used to confirm the presence of polycystic ovaries in a patient suspected of having PCOS.

Documentation Requirements

Document the reason for the ultrasound and findings.

Specialty Considerations

Endocrinologists and gynecologists should ensure imaging results are included in the patient's medical record.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of PCOS, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of associated conditions and comorbidities.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of PCOS, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of associated conditions and comorbidities.

Reimbursement & Billing Impact

reimbursement processes. It has also facilitated better tracking of associated conditions and comorbidities.

Resources

Clinical References

  • •
    Polycystic Ovary Syndrome (PCOS) - ACOG

Coding & Billing References

  • •
    Polycystic Ovary Syndrome (PCOS) - ACOG

Frequently Asked Questions

What are the common symptoms of PCOS?

Common symptoms include irregular menstrual cycles, excessive hair growth (hirsutism), acne, weight gain, and infertility.

How is PCOS diagnosed?

PCOS is diagnosed based on clinical symptoms, hormonal evaluations, and imaging studies such as pelvic ultrasound.

What are the long-term health risks associated with PCOS?

Women with PCOS are at increased risk for type 2 diabetes, cardiovascular disease, and endometrial cancer.