ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesE28.310

E28.310

Billable

Symptomatic premature menopause

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E28.310 is a billable code used to indicate a diagnosis of symptomatic premature menopause.

Key Diagnostic Point:

Symptomatic premature menopause refers to the onset of menopause before the age of 40, characterized by the cessation of menstrual periods and associated symptoms such as hot flashes, night sweats, mood changes, and vaginal dryness. This condition can result from various factors, including genetic predisposition, autoimmune disorders, surgical interventions (such as oophorectomy), or endocrine dysfunctions affecting hormone production. The premature decline in estrogen levels can lead to significant health implications, including osteoporosis and cardiovascular disease. Diagnosis typically involves a thorough clinical evaluation, including a detailed medical history, physical examination, and laboratory tests to assess hormone levels, particularly estrogen and follicle-stimulating hormone (FSH). Understanding the underlying causes, such as parathyroid, pituitary, or adrenal disorders, is crucial for effective management and treatment. Treatment options may include hormone replacement therapy (HRT) to alleviate symptoms and mitigate long-term health risks.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary causes of premature menopause.
  • Understanding the interplay of various endocrine disorders.
  • Need for comprehensive documentation of symptoms and treatment plans.
  • Potential for co-existing conditions that may complicate coding.

Audit Risk Factors

  • Inadequate documentation of symptoms and treatment.
  • Failure to document the underlying cause of menopause.
  • Misclassification of menopause type (natural vs. surgical).
  • Lack of follow-up documentation on treatment efficacy.

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Comprehensive hormonal assessments, including FSH and estrogen levels, and detailed patient history.

Common Clinical Scenarios

Patients presenting with symptoms of menopause at a young age, requiring evaluation for underlying endocrine disorders.

Billing Considerations

Endocrinologists must ensure that all potential causes of premature menopause are explored and documented.

Gynecology

Documentation Requirements

Detailed menstrual history, symptom assessment, and treatment plans.

Common Clinical Scenarios

Women seeking management for menopausal symptoms before age 40.

Billing Considerations

Gynecologists should document the impact of symptoms on quality of life and any interventions provided.

Coding Guidelines

Inclusion Criteria

Use E28.310 When
  • According to ICD
  • 10 guidelines, E28
  • 310 should be used when the patient presents with symptoms of menopause before age 40
  • It is essential to document the onset of symptoms, any relevant medical history, and the results of hormonal assessments

Exclusion Criteria

Do NOT use E28.310 When
  • Exclusion criteria include natural menopause occurring after age 40

Related ICD-10 Codes

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for follow-up visits to manage symptoms of premature menopause.

Documentation Requirements

Document the patient's symptoms, treatment plan, and any hormonal assessments.

Specialty Considerations

Endocrinologists and gynecologists should ensure comprehensive documentation to support the visit level.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like symptomatic premature menopause, improving the accuracy of data collection and reimbursement processes. It emphasizes the need for detailed documentation of symptoms and underlying causes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like symptomatic premature menopause, improving the accuracy of data collection and reimbursement processes. It emphasizes the need for detailed documentation of symptoms and underlying causes.

Reimbursement & Billing Impact

reimbursement processes. It emphasizes the need for detailed documentation of symptoms and underlying causes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common symptoms of symptomatic premature menopause?

Common symptoms include hot flashes, night sweats, mood swings, vaginal dryness, and irregular menstrual cycles. These symptoms can significantly impact quality of life and require appropriate management.