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ICD-10 Guide
ICD-10 CodesE28.39

E28.39

Billable

Other primary ovarian failure

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E28.39 is a billable code used to indicate a diagnosis of other primary ovarian failure.

Key Diagnostic Point:

Other primary ovarian failure refers to a condition characterized by the cessation of ovarian function before the age of 40, leading to a lack of estrogen production and subsequent amenorrhea. This condition can arise from various etiologies, including genetic factors, autoimmune disorders, and environmental influences. It is essential to differentiate this condition from secondary ovarian failure, which is caused by dysfunction in the hypothalamus or pituitary gland. Patients may present with symptoms such as hot flashes, night sweats, mood changes, and infertility. Hormonal imbalances, particularly low estrogen and elevated follicle-stimulating hormone (FSH) levels, are common findings in these patients. The diagnosis often requires a thorough evaluation of the patient's medical history, physical examination, and laboratory tests to assess hormone levels. Additionally, conditions affecting the parathyroid, pituitary, and adrenal glands can contribute to or complicate the presentation of primary ovarian failure, necessitating a comprehensive endocrine assessment.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation from secondary ovarian failure
  • Need for comprehensive hormonal evaluation
  • Potential overlap with other endocrine disorders
  • Variability in clinical presentation

Audit Risk Factors

  • Inadequate documentation of symptoms
  • Failure to document hormone levels
  • Lack of clarity on the underlying cause
  • Misclassification of primary vs. secondary ovarian failure

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormonal assessment and history of endocrine disorders.

Common Clinical Scenarios

Patients presenting with amenorrhea and hormonal imbalances.

Billing Considerations

Ensure all relevant endocrine tests are documented to support diagnosis.

Reproductive Medicine

Documentation Requirements

Comprehensive fertility evaluations and treatment plans.

Common Clinical Scenarios

Infertility assessments in women with suspected ovarian failure.

Billing Considerations

Document any assisted reproductive technologies used.

Coding Guidelines

Inclusion Criteria

Use E28.39 When
  • Follow official ICD
  • 10 guidelines for coding E28
  • 39, ensuring accurate documentation of the condition's etiology and associated symptoms
  • Include any relevant laboratory findings to support the diagnosis

Exclusion Criteria

Do NOT use E28.39 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

83001CPT Code

FSH test

Clinical Scenario

Used to confirm diagnosis of ovarian failure.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Endocrinologists should ensure comprehensive hormonal panels are included.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like E28.39, improving the accuracy of diagnoses and treatment plans. This specificity aids in better patient management and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like E28.39, improving the accuracy of diagnoses and treatment plans. This specificity aids in better patient management and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of primary ovarian failure?

Common causes include genetic factors, autoimmune disorders, and environmental influences. Conditions such as Turner syndrome and autoimmune oophoritis are notable examples.