Polyglandular dysfunction
Chapter 4:Endocrine, nutritional and metabolic diseases
ICD-10 E31 is a billable code used to indicate a diagnosis of polyglandular dysfunction.
Polyglandular dysfunction refers to a group of disorders characterized by the simultaneous or sequential dysfunction of two or more endocrine glands. This condition often manifests in various ways, including hormonal imbalances that can lead to growth abnormalities, puberty disorders, and immune system dysfunctions. The thymus gland, which plays a crucial role in the immune system, can also be affected, leading to increased susceptibility to infections and autoimmune diseases. In children and adolescents, polyglandular dysfunction can result in delayed or precocious puberty due to the disruption of normal hormonal signaling pathways. The interplay between the affected glands can complicate the clinical picture, making diagnosis and management challenging. Accurate coding requires a thorough understanding of the patient's clinical presentation, including any associated conditions such as autoimmune disorders or growth abnormalities. The complexity of polyglandular dysfunction lies in its multifaceted nature, necessitating careful evaluation of the patient's endocrine function and related symptoms.
Detailed endocrine evaluation, including hormone levels and gland function tests.
Patients presenting with unexplained growth abnormalities or delayed puberty.
Ensure comprehensive documentation of all affected glands and related symptoms.
Growth charts, developmental milestones, and family history of endocrine disorders.
Children with signs of precocious or delayed puberty.
Document any psychosocial impacts of growth abnormalities on the child.
Used to evaluate thyroid function in suspected polyglandular dysfunction.
Document the reason for testing and any relevant clinical findings.
Endocrinologists should ensure comprehensive evaluation of all endocrine functions.
Common symptoms include growth abnormalities, delayed or precocious puberty, fatigue, weight changes, and signs of autoimmune disorders.
