Other polyglandular dysfunction
ICD-10 E31.8 is a billable code used to indicate a diagnosis of other polyglandular dysfunction.
Other polyglandular dysfunction refers to a group of disorders characterized by the simultaneous dysfunction of multiple endocrine glands, leading to a variety of clinical manifestations. This condition can involve the thyroid, adrenal glands, pancreas, and gonads, among others. In the context of puberty disorders, polyglandular dysfunction may result in delayed or precocious puberty due to hormonal imbalances. Thymus disorders, such as thymic hypoplasia, can also be associated with polyglandular dysfunction, impacting immune function and leading to increased susceptibility to infections. Growth abnormalities may arise from deficiencies in growth hormone or other hormones regulated by the affected glands. The clinical presentation can vary widely, necessitating a thorough evaluation of hormonal levels and gland function. Diagnosis often involves a combination of clinical assessment, laboratory tests, and imaging studies to identify the specific glands involved and the nature of their dysfunction. Treatment typically focuses on hormone replacement therapy and managing the symptoms associated with the dysfunction.
Detailed hormonal assay results, imaging studies, and clinical notes on gland function.
Patients presenting with unexplained growth abnormalities or delayed puberty.
Ensure all affected glands are documented to support the diagnosis.
Growth charts, developmental milestones, and family history of endocrine disorders.
Children with signs of precocious puberty or growth retardation.
Consider age-related norms for hormone levels and growth patterns.
Used to evaluate thyroid function in patients with suspected polyglandular dysfunction.
Document the rationale for testing and results.
Endocrinologists should ensure comprehensive testing of all relevant hormones.
Common symptoms include growth abnormalities, delayed or precocious puberty, fatigue, weight changes, and increased susceptibility to infections due to immune dysfunction.
