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ICD-10 Guide
ICD-10 CodesE31.9

E31.9

Billable

Polyglandular dysfunction, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E31.9 is a billable code used to indicate a diagnosis of polyglandular dysfunction, unspecified.

Key Diagnostic Point:

Polyglandular dysfunction refers to a condition where multiple endocrine glands fail to function properly, leading to a variety of hormonal imbalances. This dysfunction can manifest in various ways, including growth abnormalities, puberty disorders, and thymus disorders. In children and adolescents, polyglandular dysfunction may result in delayed or precocious puberty due to the disruption of the hypothalamic-pituitary-gonadal axis. Additionally, thymus disorders can lead to immune deficiencies, as the thymus plays a crucial role in T-cell maturation. Growth abnormalities may arise from insufficient hormone production, particularly growth hormone, thyroid hormones, and sex steroids. The unspecified nature of this code indicates that the specific glands involved or the exact nature of the dysfunction is not clearly defined, making it essential for healthcare providers to document clinical findings thoroughly to guide appropriate treatment and management.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of potential underlying causes
  • Overlap with other endocrine disorders
  • Need for comprehensive documentation
  • Potential for multiple gland involvement

Audit Risk Factors

  • Insufficient documentation of gland involvement
  • Inconsistent clinical findings
  • Lack of follow-up notes
  • Misinterpretation of symptoms

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormonal assessment and gland function tests.

Common Clinical Scenarios

Patients presenting with unexplained growth delays or hormonal imbalances.

Billing Considerations

Ensure all relevant lab results and imaging studies are included in the documentation.

Pediatrics

Documentation Requirements

Growth charts, puberty assessment, and family history of endocrine disorders.

Common Clinical Scenarios

Children with delayed puberty or abnormal growth patterns.

Billing Considerations

Document developmental milestones and any psychosocial factors affecting growth.

Coding Guidelines

Inclusion Criteria

Use E31.9 When
  • According to ICD
  • 10 guidelines, E31
  • 9 should be used when the specific gland dysfunction is not identified
  • Coders should ensure that the diagnosis is supported by clinical documentation and that other potential causes of symptoms are ruled out

Exclusion Criteria

Do NOT use E31.9 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

83001CPT Code

Thyroid stimulating hormone (TSH) test

Clinical Scenario

Used to evaluate thyroid function in patients with suspected polyglandular dysfunction.

Documentation Requirements

Document the reason for the test and any relevant clinical findings.

Specialty Considerations

Endocrinologists should ensure comprehensive thyroid evaluations are included.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of polyglandular dysfunction, enabling better tracking of patient outcomes and resource allocation. However, the unspecified nature of E31.9 may lead to challenges in data analysis and treatment planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of polyglandular dysfunction, enabling better tracking of patient outcomes and resource allocation. However, the unspecified nature of E31.9 may lead to challenges in data analysis and treatment planning.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of polyglandular dysfunction, enabling better tracking of patient outcomes and resource allocation. However, the unspecified nature of E31.9 may lead to challenges in data analysis and treatment planning.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common symptoms of polyglandular dysfunction?

Common symptoms include growth abnormalities, delayed or precocious puberty, fatigue, weight changes, and recurrent infections due to immune dysfunction.