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ICD-10 Guide
ICD-10 CodesChapter 4: Endocrine, nutritional and metabolic diseasesE35

E35

Billable

Disorders of endocrine glands in diseases classified elsewhere

Chapter 4:Endocrine, nutritional and metabolic diseases

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E35 is a billable code used to indicate a diagnosis of disorders of endocrine glands in diseases classified elsewhere.

Key Diagnostic Point:

E35 encompasses a variety of disorders affecting the endocrine glands that are secondary to other diseases. This includes conditions related to puberty disorders, such as precocious or delayed puberty, which can arise from hormonal imbalances or underlying health issues. Polyglandular dysfunction, where multiple endocrine glands are affected, may also fall under this code, often seen in autoimmune conditions. Thymus disorders, such as thymic hyperplasia or hypoplasia, can impact endocrine function and are classified here as well. Growth abnormalities, including growth hormone deficiencies or excesses, are also relevant, as they can lead to significant health issues if not properly managed. Accurate coding requires a thorough understanding of the underlying conditions and their impact on endocrine function, as well as the specific clinical context of the patient.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying conditions leading to endocrine disorders
  • Need for comprehensive patient history to determine causation
  • Potential overlap with other endocrine codes
  • Variability in clinical presentation and symptoms

Audit Risk Factors

  • Inadequate documentation of the primary disease
  • Failure to specify the type of endocrine disorder
  • Misclassification of polyglandular syndromes
  • Lack of clarity in the relationship between conditions

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed patient history, lab results, and imaging studies.

Common Clinical Scenarios

Patients with autoimmune disorders presenting with multiple endocrine dysfunctions.

Billing Considerations

Ensure clear documentation of all affected glands and their specific disorders.

Pediatrics

Documentation Requirements

Growth charts, hormonal assay results, and developmental history.

Common Clinical Scenarios

Children presenting with delayed or precocious puberty.

Billing Considerations

Document age-specific growth patterns and any associated symptoms.

Coding Guidelines

Inclusion Criteria

Use E35 When
  • Follow official ICD
  • 10 coding guidelines, ensuring that the primary disease is well
  • documented
  • E35 should be used when the endocrine disorder is a direct result of another classified disease
  • Ensure to review inclusion criteria for specific conditions that may fall under this code

Exclusion Criteria

Do NOT use E35 When
No specific exclusions found.

Related CPT Codes

83001CPT Code

Thyroid-stimulating hormone (TSH) test

Clinical Scenario

Used to evaluate thyroid function in patients with suspected endocrine disorders.

Documentation Requirements

Document the reason for the test and any relevant clinical findings.

Specialty Considerations

Endocrinologists should ensure comprehensive lab results are included.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of endocrine disorders, improving the ability to capture the nuances of conditions like E35. This specificity aids in better patient management and resource allocation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of endocrine disorders, improving the ability to capture the nuances of conditions like E35. This specificity aids in better patient management and resource allocation.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of endocrine disorders, improving the ability to capture the nuances of conditions like E35. This specificity aids in better patient management and resource allocation.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What types of conditions are classified under E35?

E35 includes disorders of endocrine glands that are secondary to other diseases, such as puberty disorders, polyglandular dysfunction, thymus disorders, and growth abnormalities.