Megavitamin-B6 syndrome
ICD-10 E67.2 is a billable code used to indicate a diagnosis of megavitamin-b6 syndrome.
Megavitamin-B6 syndrome is a rare condition resulting from excessive intake of vitamin B6 (pyridoxine), typically through supplementation. This syndrome is characterized by neurological symptoms such as sensory neuropathy, ataxia, and in severe cases, loss of proprioception. Patients may also experience gastrointestinal disturbances, including nausea and abdominal pain. The condition arises when vitamin B6 levels exceed the body's requirements, leading to toxicity. Chronic high doses can lead to irreversible nerve damage, emphasizing the importance of monitoring vitamin intake, especially in individuals taking supplements for various health conditions. Diagnosis is primarily clinical, supported by a thorough history of dietary intake and supplementation. Management involves cessation of vitamin B6 supplementation and symptomatic treatment. Awareness of this syndrome is crucial, particularly in the context of weight management and obesity, where individuals may resort to high-dose vitamins in an attempt to enhance metabolic processes or weight loss.
Detailed dietary history and supplementation records.
Patients presenting with neuropathy and a history of high-dose vitamin supplementation.
Ensure clear documentation of dietary habits to support diagnosis.
Neurological assessments and symptomatology documentation.
Patients with unexplained neuropathic symptoms and potential vitamin toxicity.
Differentiation from other neuropathies is critical for accurate coding.
Used for follow-up visits to assess symptoms related to megavitamin-B6 syndrome.
Document history of vitamin intake and neurological assessments.
Nutrition and neurology specialties should coordinate documentation.
Symptoms include sensory neuropathy, ataxia, gastrointestinal disturbances, and in severe cases, loss of proprioception.
Diagnosis is based on clinical history of high vitamin B6 intake, symptomatology, and exclusion of other neuropathies.
The primary treatment is to discontinue vitamin B6 supplementation and manage symptoms as they arise.
