Other secondary carnitine deficiency
ICD-10 E71.448 is a billable code used to indicate a diagnosis of other secondary carnitine deficiency.
Other secondary carnitine deficiency refers to a condition where there is an inadequate supply of carnitine due to secondary causes, such as metabolic disorders, chronic diseases, or certain medications. Carnitine is essential for the transport of long-chain fatty acids into the mitochondria for energy production. Deficiencies can lead to symptoms such as muscle weakness, cardiomyopathy, hypoglycemia, and liver dysfunction. This condition can arise from various underlying issues, including malnutrition, chronic renal failure, or the use of certain drugs that interfere with carnitine metabolism. Diagnosis typically involves biochemical tests to measure carnitine levels in the blood and urine, alongside a thorough clinical evaluation to identify the underlying cause. Management may include dietary modifications, supplementation with carnitine, and addressing the primary condition contributing to the deficiency. Understanding the metabolic pathways and the role of carnitine in fatty acid metabolism is crucial for effective diagnosis and treatment.
Detailed metabolic assessments, including biochemical tests and patient history.
Patients presenting with unexplained muscle weakness or cardiomyopathy.
Ensure comprehensive metabolic panels are documented to support diagnosis.
Documentation of renal function tests and any medications affecting carnitine levels.
Patients with chronic kidney disease experiencing symptoms of carnitine deficiency.
Consideration of dialysis effects on carnitine levels and supplementation needs.
Used to confirm diagnosis of carnitine deficiency.
Document the reason for testing and any relevant clinical findings.
Metabolic specialists should ensure comprehensive metabolic evaluations are performed.
Common causes include chronic kidney disease, malnutrition, certain medications, and metabolic disorders that affect carnitine metabolism.
