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ICD-10 Guide
ICD-10 CodesG04.3

G04.3

Billable

Acute necrotizing hemorrhagic encephalopathy

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 G04.3 is a billable code used to indicate a diagnosis of acute necrotizing hemorrhagic encephalopathy.

Key Diagnostic Point:

Acute necrotizing hemorrhagic encephalopathy (ANHE) is a rare but severe neurological condition characterized by rapid onset of encephalopathy, often following a viral infection. It is marked by extensive necrosis and hemorrhage in the brain, particularly affecting the thalamus and brainstem. Clinically, patients may present with altered mental status, seizures, and focal neurological deficits. The condition is often associated with viral infections, such as influenza or other respiratory viruses, and can lead to significant morbidity and mortality. Diagnosis typically involves neuroimaging, such as MRI, which reveals characteristic findings of bilateral thalamic lesions and hemorrhagic changes. Management is primarily supportive, focusing on controlling symptoms and preventing complications. Early recognition and intervention are crucial for improving outcomes, as the rapid progression of the disease can lead to severe neurological impairment or death.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires detailed clinical documentation to support diagnosis.
  • Differentiation from other encephalopathies can be challenging.
  • Potential for misdiagnosis due to overlapping symptoms with other CNS infections.
  • Need for precise coding based on imaging findings and clinical presentation.

Audit Risk Factors

  • Inadequate documentation of clinical findings.
  • Failure to specify the viral etiology when applicable.
  • Misinterpretation of imaging results leading to incorrect coding.
  • Lack of follow-up documentation to support ongoing treatment.

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed neurological examination findings, imaging results, and treatment plans.

Common Clinical Scenarios

Patients presenting with acute neurological symptoms following viral infections.

Billing Considerations

Ensure that all neurological deficits and imaging findings are documented to support the diagnosis.

Infectious Disease

Documentation Requirements

Documentation of the infectious etiology, laboratory results, and treatment response.

Common Clinical Scenarios

Patients with encephalopathy following viral infections requiring infectious disease consultation.

Billing Considerations

Document the timeline of infection and neurological symptoms to establish causality.

Coding Guidelines

Inclusion Criteria

Use G04.3 When
  • According to ICD
  • 10 coding guidelines, G04
  • 3 should be used when there is clear documentation of acute necrotizing hemorrhagic encephalopathy, supported by imaging findings

Exclusion Criteria

Do NOT use G04.3 When
  • It is essential to exclude other causes of encephalopathy and document any underlying viral infections

Related ICD-10 Codes

Related CPT Codes

70450CPT Code

CT scan of the head

Clinical Scenario

Used to evaluate for hemorrhagic changes in the brain.

Documentation Requirements

Document indications for imaging and findings.

Specialty Considerations

Neurology should correlate imaging findings with clinical symptoms.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like acute necrotizing hemorrhagic encephalopathy, improving data accuracy and facilitating better tracking of this rare condition.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like acute necrotizing hemorrhagic encephalopathy, improving data accuracy and facilitating better tracking of this rare condition.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like acute necrotizing hemorrhagic encephalopathy, improving data accuracy and facilitating better tracking of this rare condition.

Resources

Clinical References

  • •
    CDC - Encephalitis

Coding & Billing References

  • •
    CDC - Encephalitis

Frequently Asked Questions

What are the common causes of acute necrotizing hemorrhagic encephalopathy?

Common causes include viral infections, particularly influenza and other respiratory viruses, which can trigger an inflammatory response leading to this condition.