ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesG04.81

G04.81

Billable

Other encephalitis and encephalomyelitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 G04.81 is a billable code used to indicate a diagnosis of other encephalitis and encephalomyelitis.

Key Diagnostic Point:

Other encephalitis and encephalomyelitis refers to a group of inflammatory conditions affecting the brain and spinal cord that are not classified under specific viral or bacterial etiologies. These conditions can arise from various infectious agents, autoimmune responses, or post-infectious processes. Symptoms may include fever, headache, confusion, seizures, and neurological deficits. Diagnosis typically involves clinical evaluation, imaging studies such as MRI, and laboratory tests including lumbar puncture for cerebrospinal fluid analysis. Treatment often includes antiviral medications, corticosteroids, and supportive care. The complexity of diagnosing and coding these conditions arises from the need to differentiate them from other CNS infections, such as meningitis and brain abscesses, and to identify the underlying cause of the encephalitis or encephalomyelitis. Accurate coding is essential for appropriate management and reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of potential underlying causes (viral, autoimmune, etc.)
  • Need for differential diagnosis with other CNS conditions
  • Variability in clinical presentation and severity
  • Potential for overlapping symptoms with other neurological disorders

Audit Risk Factors

  • Inadequate documentation of the underlying cause
  • Failure to differentiate from other CNS infections
  • Lack of clarity in clinical notes regarding symptoms
  • Misuse of related codes leading to incorrect billing

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed clinical notes including symptoms, diagnostic tests performed, and treatment plans.

Common Clinical Scenarios

Patients presenting with acute neurological symptoms, suspected viral infections, or post-infectious complications.

Billing Considerations

Neurologists must ensure comprehensive documentation to support the diagnosis and differentiate from other conditions.

Infectious Disease

Documentation Requirements

Thorough history of exposure, laboratory results, and treatment response.

Common Clinical Scenarios

Patients with suspected infectious etiologies of encephalitis, including travel history or immunocompromised status.

Billing Considerations

Infectious disease specialists should document the specific infectious agent when known to support coding.

Coding Guidelines

Inclusion Criteria

Use G04.81 When
  • Official coding guidelines for G04
  • 81 include ensuring that the diagnosis is supported by clinical documentation, differentiating from other encephalitis codes, and adhering to the inclusion criteria for other encephalitis and encephalomyelitis

Exclusion Criteria

Do NOT use G04.81 When
  • Exclusion criteria must also be considered to avoid misclassification

Related ICD-10 Codes

Related CPT Codes

62270CPT Code

Lumbar puncture

Clinical Scenario

Used to obtain cerebrospinal fluid for analysis in suspected encephalitis cases.

Documentation Requirements

Document indication for the procedure, findings, and any complications.

Specialty Considerations

Neurologists should ensure that the necessity of the lumbar puncture is clearly stated.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of encephalitis and encephalomyelitis, improving the accuracy of diagnoses and treatment tracking. G04.81 provides a means to capture cases that do not fit neatly into other categories, enhancing data collection and analysis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of encephalitis and encephalomyelitis, improving the accuracy of diagnoses and treatment tracking. G04.81 provides a means to capture cases that do not fit neatly into other categories, enhancing data collection and analysis.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of G04.81?

Common causes include viral infections, autoimmune disorders, and post-infectious reactions. Specific viral agents may not always be identified, necessitating the use of G04.81.

How can I differentiate G04.81 from other encephalitis codes?

G04.81 is used when the specific cause of encephalitis is unknown or does not fit into other defined categories. Documentation should clarify the clinical context.