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ICD-10 Guide
ICD-10 CodesG21.19

G21.19

Billable

Other drug induced secondary parkinsonism

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 G21.19 is a billable code used to indicate a diagnosis of other drug induced secondary parkinsonism.

Key Diagnostic Point:

Other drug induced secondary parkinsonism refers to a form of parkinsonism that is caused by the use of certain medications, particularly those that affect dopaminergic pathways in the brain. This condition is characterized by symptoms similar to Parkinson's disease, including tremors, rigidity, bradykinesia, and postural instability. Unlike primary Parkinson's disease, which is idiopathic, drug-induced parkinsonism is a secondary condition that arises from the pharmacological effects of specific drugs, particularly antipsychotics, antiemetics, and certain antidepressants. The pathophysiology involves the blockade of dopamine receptors, leading to an imbalance in the dopaminergic and cholinergic systems. Clinicians must carefully evaluate the patient's medication history and consider the timing of symptom onset in relation to drug exposure. Management typically involves discontinuation or adjustment of the offending medication, and in some cases, the use of anticholinergic agents or dopaminergic medications may be warranted to alleviate symptoms. Accurate diagnosis and coding are essential to ensure appropriate treatment and reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary parkinsonism
  • Identifying the specific drug responsible for symptoms
  • Understanding the timeline of medication use and symptom onset
  • Documenting the patient's complete medication history

Audit Risk Factors

  • Inadequate documentation of medication history
  • Failure to specify the drug causing the parkinsonism
  • Misdiagnosis of primary Parkinson's disease instead of secondary
  • Lack of clear correlation between drug use and symptom onset

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed history of neurological symptoms, medication history, and response to treatment.

Common Clinical Scenarios

Patients presenting with new-onset parkinsonism after starting antipsychotic medications.

Billing Considerations

Neurologists must differentiate between primary and secondary causes of parkinsonism.

Psychiatry

Documentation Requirements

Thorough documentation of psychiatric medications prescribed and their dosages.

Common Clinical Scenarios

Patients experiencing parkinsonism symptoms while on antipsychotic medications.

Billing Considerations

Psychiatrists should monitor for extrapyramidal side effects and adjust medications accordingly.

Coding Guidelines

Inclusion Criteria

Use G21.19 When
  • According to ICD
  • 10 guidelines, G21
  • 19 should be used when parkinsonism is clearly linked to drug exposure
  • Coders must ensure that the documentation supports the diagnosis of drug
  • induced parkinsonism and not primary Parkinson's disease

Exclusion Criteria

Do NOT use G21.19 When
  • Exclusion criteria include cases where parkinsonism is due to other neurological conditions

Related ICD-10 Codes

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for follow-up visits to assess medication effects and adjust treatment.

Documentation Requirements

Document the patient's medication history, symptoms, and treatment response.

Specialty Considerations

Neurologists and psychiatrists should ensure comprehensive notes on medication management.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of drug-induced parkinsonism, improving the accuracy of diagnosis and treatment tracking. This specificity aids in better understanding the prevalence and management of drug-induced movement disorders.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of drug-induced parkinsonism, improving the accuracy of diagnosis and treatment tracking. This specificity aids in better understanding the prevalence and management of drug-induced movement disorders.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What medications are commonly associated with G21.19?

Common medications include antipsychotics like haloperidol and risperidone, antiemetics like metoclopramide, and certain antidepressants. It's crucial to review the patient's medication history to identify potential causes.