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ICD-10 Guide
ICD-10 CodesG21.2

G21.2

Billable

Secondary parkinsonism due to other external agents

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 G21.2 is a billable code used to indicate a diagnosis of secondary parkinsonism due to other external agents.

Key Diagnostic Point:

Secondary parkinsonism refers to a group of movement disorders that mimic the symptoms of Parkinson's disease but are caused by external factors rather than primary neurodegenerative processes. This condition can arise from various external agents, including certain medications, toxins, or infections. Commonly implicated agents include antipsychotic medications, which can induce extrapyramidal symptoms, and neurotoxins such as carbon monoxide or manganese. Patients may present with bradykinesia, rigidity, and tremors, similar to those seen in idiopathic Parkinson's disease. However, the distinguishing factor is the identifiable external cause. Diagnosis typically involves a thorough patient history, including medication review and exposure history, along with neurological examination. Management focuses on addressing the underlying cause, which may involve discontinuation of offending agents and symptomatic treatment with dopaminergic medications or other therapies. Understanding the etiology is crucial for effective treatment and prognosis, as secondary parkinsonism may be reversible if the causative agent is removed.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Identifying the specific external agent causing parkinsonism.
  • Differentiating between primary and secondary parkinsonism.
  • Documenting the patient's medication history accurately.
  • Understanding the nuances of movement disorders and their presentations.

Audit Risk Factors

  • Inadequate documentation of the external agent.
  • Failure to differentiate from primary parkinsonism.
  • Misclassification of symptoms as idiopathic.
  • Lack of comprehensive medication history.

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed patient history, including medication and exposure history, neurological examination findings.

Common Clinical Scenarios

Patients presenting with new-onset parkinsonism after starting antipsychotic medications.

Billing Considerations

Consideration of the timeline of symptom onset in relation to exposure to external agents.

Psychiatry

Documentation Requirements

Documentation of psychiatric medications prescribed and their potential side effects.

Common Clinical Scenarios

Patients experiencing extrapyramidal symptoms while on antipsychotic therapy.

Billing Considerations

Monitoring for movement disorders in patients receiving long-term antipsychotic treatment.

Coding Guidelines

Inclusion Criteria

Use G21.2 When
  • According to ICD
  • 10 guidelines, G21
  • 2 should be used when parkinsonism is clearly linked to an external agent
  • Coders must ensure that the external cause is documented and that the symptoms are not due to primary Parkinson's disease or other movement disorders

Exclusion Criteria

Do NOT use G21.2 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for follow-up visits for patients with secondary parkinsonism.

Documentation Requirements

Document the patient's history, medication review, and neurological examination findings.

Specialty Considerations

Neurologists should focus on the impact of external agents on symptoms.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of secondary parkinsonism, improving the ability to track and manage cases related to external agents. This specificity aids in research and treatment planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of secondary parkinsonism, improving the ability to track and manage cases related to external agents. This specificity aids in research and treatment planning.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common external agents that can cause secondary parkinsonism?

Common external agents include antipsychotic medications, certain antiemetics, and neurotoxins such as carbon monoxide and manganese.

How can secondary parkinsonism be differentiated from idiopathic Parkinson's disease?

Secondary parkinsonism can be differentiated by identifying an external cause, such as medication history or toxin exposure, and by the timeline of symptom onset.