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ICD-10 Guide
ICD-10 CodesG43.61

G43.61

Billable

Persistent migraine aura with cerebral infarction, intractable

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 G43.61 is a billable code used to indicate a diagnosis of persistent migraine aura with cerebral infarction, intractable.

Key Diagnostic Point:

Persistent migraine aura with cerebral infarction, intractable, is a rare but serious condition characterized by prolonged neurological symptoms that resemble a migraine aura, such as visual disturbances, sensory changes, or speech difficulties, which persist for more than one week and are accompanied by cerebral infarction. This condition can lead to significant morbidity due to the risk of stroke and other complications. Patients may experience severe, recurrent headaches that do not respond to standard migraine treatments, making the condition intractable. The pathophysiology involves a complex interplay of vascular and neurological factors, including cortical spreading depression and ischemic changes in the brain. Diagnosis typically requires a thorough clinical evaluation, imaging studies such as MRI or CT scans to identify infarction, and exclusion of other causes of persistent aura symptoms. Management may involve acute treatment of headaches, preventive therapies, and addressing risk factors for stroke.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Differentiating between migraine aura and other neurological conditions
  • Need for imaging studies to confirm cerebral infarction
  • Intractability of symptoms complicating treatment options
  • Potential overlap with other headache disorders

Audit Risk Factors

  • Inadequate documentation of persistent symptoms
  • Failure to provide imaging results confirming cerebral infarction
  • Misclassification of intractable migraines
  • Lack of comprehensive treatment history

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed neurological examination findings, imaging results, and treatment history.

Common Clinical Scenarios

Patients presenting with prolonged aura symptoms and headache, requiring differential diagnosis from stroke.

Billing Considerations

Ensure clear documentation of symptom duration and response to treatments.

Primary Care

Documentation Requirements

Comprehensive patient history, including headache frequency, severity, and associated symptoms.

Common Clinical Scenarios

Patients with recurrent headaches and aura symptoms seeking management.

Billing Considerations

Documenting referrals to specialists and any imaging studies ordered.

Coding Guidelines

Inclusion Criteria

Use G43.61 When
  • According to ICD
  • 10 guidelines, G43
  • 61 should be used when there is clear documentation of persistent migraine aura symptoms lasting longer than one week, accompanied by evidence of cerebral infarction

Exclusion Criteria

Do NOT use G43.61 When
  • It is essential to exclude other causes of similar symptoms

Related ICD-10 Codes

Related CPT Codes

99214CPT Code

Established patient office visit, level 4

Clinical Scenario

Used for follow-up visits for patients with persistent migraine aura.

Documentation Requirements

Detailed history and examination findings related to headache and aura symptoms.

Specialty Considerations

Neurologists may require additional documentation of neurological assessments.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of migraine-related conditions, including the differentiation of persistent migraine aura with cerebral infarction, which was less clearly defined in ICD-9.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of migraine-related conditions, including the differentiation of persistent migraine aura with cerebral infarction, which was less clearly defined in ICD-9.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    American Migraine Foundation

Coding & Billing References

  • •
    American Migraine Foundation

Frequently Asked Questions

What distinguishes G43.61 from other migraine codes?

G43.61 specifically indicates the presence of persistent aura symptoms lasting longer than one week, accompanied by cerebral infarction, making it distinct from other migraine codes that do not include these complications.