Drug-induced myopathy
ICD-10 G72.0 is a billable code used to indicate a diagnosis of drug-induced myopathy.
Drug-induced myopathy is a condition characterized by muscle weakness and dysfunction resulting from the use of certain medications. This condition can arise from various drug classes, including corticosteroids, statins, and certain antiretrovirals. Patients may present with symptoms such as muscle pain, weakness, and fatigue, which can significantly impact their quality of life. The pathophysiology often involves direct muscle toxicity or an immune-mediated response triggered by the drug. Diagnosis typically requires a thorough patient history, including a review of medications, physical examination, and laboratory tests such as creatine kinase levels. Electromyography (EMG) and muscle biopsy may also be utilized to confirm the diagnosis and rule out other myopathies. Management involves discontinuation of the offending agent and supportive care, with some cases requiring corticosteroids or other immunosuppressive therapies. Understanding the relationship between drug exposure and muscle symptoms is crucial for effective diagnosis and treatment.
Detailed history of medication use, symptom onset, and neurological examination findings.
Patients presenting with unexplained muscle weakness after starting new medications.
Consideration of other neuromuscular disorders that may mimic drug-induced myopathy.
Comprehensive review of autoimmune conditions and medications that may contribute to myopathy.
Patients with autoimmune diseases on immunosuppressive therapy presenting with muscle weakness.
Differentiating between drug-induced myopathy and myopathy related to the underlying autoimmune condition.
Used to evaluate muscle function in patients suspected of having drug-induced myopathy.
Document the reason for the EMG, including symptoms and medication history.
Neurologists should ensure comprehensive documentation linking EMG findings to the diagnosis.
Common drugs include statins, corticosteroids, and certain antiretroviral medications. It is essential to review the patient's medication history to identify potential culprits.
