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v1.0.0
ICD-10 Guide
ICD-10 CodesG93.7

G93.7

Billable

Reye's syndrome

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 G93.7 is a billable code used to indicate a diagnosis of reye's syndrome.

Key Diagnostic Point:

Reye's syndrome is a rare but serious condition that primarily affects children and adolescents, characterized by acute encephalopathy and fatty degeneration of the liver. It typically follows a viral infection, such as influenza or chickenpox, and is often associated with the use of aspirin during these infections. Clinically, Reye's syndrome presents with a rapid onset of symptoms including vomiting, confusion, seizures, and loss of consciousness. The pathophysiology involves mitochondrial dysfunction leading to impaired fatty acid oxidation and accumulation of toxic metabolites. Diagnosis is based on clinical presentation, laboratory findings, and imaging studies that may reveal cerebral edema or liver dysfunction. Early recognition and management are crucial, as the condition can progress to severe neurological impairment or death if not treated promptly. Supportive care, including monitoring of intracranial pressure and liver function, is essential in the management of affected patients.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires knowledge of specific clinical presentation and history.
  • Differentiation from other encephalopathies can be challenging.
  • Documentation must clearly indicate the association with viral infections.
  • Potential for misdiagnosis with other neurological disorders.

Audit Risk Factors

  • Inadequate documentation of viral infection history.
  • Failure to document the acute onset of symptoms.
  • Misclassification of the syndrome as a different neurological disorder.
  • Lack of supporting lab results or imaging studies.

Specialty Focus

Medical Specialties

Pediatrics

Documentation Requirements

Detailed history of recent viral infections, symptom onset, and neurological assessment.

Common Clinical Scenarios

Children presenting with vomiting and altered mental status after a viral illness.

Billing Considerations

Consideration of aspirin use in the child's medical history is crucial.

Neurology

Documentation Requirements

Neurological examination findings, imaging results, and differential diagnosis considerations.

Common Clinical Scenarios

Patients with unexplained encephalopathy and liver dysfunction.

Billing Considerations

Differentiating Reye's syndrome from other causes of encephalopathy is essential.

Coding Guidelines

Inclusion Criteria

Use G93.7 When
  • According to ICD
  • 10 coding guidelines, G93
  • 7 should be used when the clinical criteria for Reye's syndrome are met, including acute encephalopathy and liver dysfunction following a viral infection

Exclusion Criteria

Do NOT use G93.7 When
  • Exclusion criteria include other known causes of encephalopathy

Related ICD-10 Codes

Related CPT Codes

99284CPT Code

Emergency department visit, high severity

Clinical Scenario

Used when a child presents with severe symptoms of Reye's syndrome.

Documentation Requirements

Document the severity of symptoms and any interventions performed.

Specialty Considerations

Pediatric emergency care protocols should be followed.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of Reye's syndrome, improving the accuracy of data collection and analysis related to this rare condition.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of Reye's syndrome, improving the accuracy of data collection and analysis related to this rare condition.

Reimbursement & Billing Impact

reimbursement and to avoid audits.

Resources

Clinical References

  • •
    Reye's Syndrome Foundation

Coding & Billing References

  • •
    Reye's Syndrome Foundation

Frequently Asked Questions

What are the common symptoms of Reye's syndrome?

Common symptoms include vomiting, confusion, seizures, and loss of consciousness, typically following a viral infection.

How is Reye's syndrome diagnosed?

Diagnosis is based on clinical presentation, laboratory findings of liver dysfunction, and imaging studies showing cerebral edema.